tetano
Editor, Senior Moderator
Case Rep Womens Health
. 2022 Jul;35:e00420.
doi: 10.1016/j.crwh.2022.e00420. Epub 2022 May 10.
Multisystem inflammatory syndrome in children (MIS-C) in pregnancy can mimic new-onset pre-eclampsia: A case report
Khrystyna Levytska[SUP] 1 [/SUP], Lorene Temming[SUP] 2 [/SUP], Jason Dranove[SUP] 3 [/SUP], Ngina Connors[SUP] 2 [/SUP], Rebecca Pollack[SUP] 2 [/SUP]
Affiliations
Abstract
Introduction: Pregnant women affected by coronavirus disease 2019 (COVID-19) are at increased risk of severe disease, admission to an intensive care unit, and adverse pregnancy outcomes. In contrast, children typically experience a mild form of COVID-19. Nonetheless, there is a risk of multisystem inflammatory syndrome in children (MIS-C) following a SARS-CoV-2 infection.
Case: A healthy 16-year-old, G1P0, presented with MIS-C in the second trimester and was treated with intravenous immunoglobulin. She subsequently developed transient mild hypertension, proteinuria, and transaminitis, which ultimately was thought to be secondary to MIS-C rather than pre-eclampsia.
Discussion: MIS-C is an important COVID-19 complication in pediatric patients. This case offers guidance on expectant management of hypertension, transaminitis, and proteinuria during an episode of MIS-C in pregnant patients, as opposed to preterm delivery for a misdiagnosis of severe pre-eclampsia.
Keywords: Hypertension; Multisystem inflammatory syndrome in children; Pediatric pregnancy; Proteinuria; Transaminitis.
. 2022 Jul;35:e00420.
doi: 10.1016/j.crwh.2022.e00420. Epub 2022 May 10.
Multisystem inflammatory syndrome in children (MIS-C) in pregnancy can mimic new-onset pre-eclampsia: A case report
Khrystyna Levytska[SUP] 1 [/SUP], Lorene Temming[SUP] 2 [/SUP], Jason Dranove[SUP] 3 [/SUP], Ngina Connors[SUP] 2 [/SUP], Rebecca Pollack[SUP] 2 [/SUP]
Affiliations
- PMID: 35574175
- PMCID: PMC9085464
- DOI: 10.1016/j.crwh.2022.e00420
Abstract
Introduction: Pregnant women affected by coronavirus disease 2019 (COVID-19) are at increased risk of severe disease, admission to an intensive care unit, and adverse pregnancy outcomes. In contrast, children typically experience a mild form of COVID-19. Nonetheless, there is a risk of multisystem inflammatory syndrome in children (MIS-C) following a SARS-CoV-2 infection.
Case: A healthy 16-year-old, G1P0, presented with MIS-C in the second trimester and was treated with intravenous immunoglobulin. She subsequently developed transient mild hypertension, proteinuria, and transaminitis, which ultimately was thought to be secondary to MIS-C rather than pre-eclampsia.
Discussion: MIS-C is an important COVID-19 complication in pediatric patients. This case offers guidance on expectant management of hypertension, transaminitis, and proteinuria during an episode of MIS-C in pregnant patients, as opposed to preterm delivery for a misdiagnosis of severe pre-eclampsia.
Keywords: Hypertension; Multisystem inflammatory syndrome in children; Pediatric pregnancy; Proteinuria; Transaminitis.