tetano
Editor, Senior Moderator
Can J Cardiol
. 2020 May 12;S0828-282X(20)30449-9.
doi: 10.1016/j.cjca.2020.05.005. Online ahead of print.
Hemodynamic Collapse After Influenza Vaccination: A Vaccine-Induced Fulminant Myocarditis?
Nobutaka Nagano[SUP] 1 [/SUP], Toshiyuki Yano[SUP] 2 [/SUP], M D Yugo Fujita[SUP] 1 [/SUP], Masayuki Koyama[SUP] 3 [/SUP], Ryo Hasegawa[SUP] 1 [/SUP], Jun Nakata[SUP] 1 [/SUP], Ryo Nishikawa[SUP] 1 [/SUP], Naoto Murakami[SUP] 1 [/SUP], Takefumi Fujito[SUP] 1 [/SUP], Atsushi Mochizuki[SUP] 1 [/SUP], Hidemichi Kouzu[SUP] 1 [/SUP], Atsuko Muranaka[SUP] 1 [/SUP], Nobuaki Kokubu[SUP] 1 [/SUP], Tetsuji Miura[SUP] 1 [/SUP]
Affiliations
Abstract
A 14-year-old girl with cardiopulmonary arrest was referred to our hospital. She had received an injection of inactivated influenza vaccine 7 days before the referral. Her cardiac rhythm was pulseless wide QRS tachycardia, and mechanical circulatory support was immediately commenced. Results of endomyocardial biopsy showed that there was massive infiltration of CD3- and CD68-positive cells, and various degrees of cardiomyocyte necrosis in all of three endomyocardial specimens, while infiltration of eosinophils or giant cells was not observed. A histological diagnosis of lymphocytic myocarditis was made. Acute myocarditis is a rare but potentially fatal complication of the influenza vaccination.
Keywords: cardiopulmonary arrest; influenza; myocarditis; vaccination.
. 2020 May 12;S0828-282X(20)30449-9.
doi: 10.1016/j.cjca.2020.05.005. Online ahead of print.
Hemodynamic Collapse After Influenza Vaccination: A Vaccine-Induced Fulminant Myocarditis?
Nobutaka Nagano[SUP] 1 [/SUP], Toshiyuki Yano[SUP] 2 [/SUP], M D Yugo Fujita[SUP] 1 [/SUP], Masayuki Koyama[SUP] 3 [/SUP], Ryo Hasegawa[SUP] 1 [/SUP], Jun Nakata[SUP] 1 [/SUP], Ryo Nishikawa[SUP] 1 [/SUP], Naoto Murakami[SUP] 1 [/SUP], Takefumi Fujito[SUP] 1 [/SUP], Atsushi Mochizuki[SUP] 1 [/SUP], Hidemichi Kouzu[SUP] 1 [/SUP], Atsuko Muranaka[SUP] 1 [/SUP], Nobuaki Kokubu[SUP] 1 [/SUP], Tetsuji Miura[SUP] 1 [/SUP]
Affiliations
- PMID: 32413549
- DOI: 10.1016/j.cjca.2020.05.005
Abstract
A 14-year-old girl with cardiopulmonary arrest was referred to our hospital. She had received an injection of inactivated influenza vaccine 7 days before the referral. Her cardiac rhythm was pulseless wide QRS tachycardia, and mechanical circulatory support was immediately commenced. Results of endomyocardial biopsy showed that there was massive infiltration of CD3- and CD68-positive cells, and various degrees of cardiomyocyte necrosis in all of three endomyocardial specimens, while infiltration of eosinophils or giant cells was not observed. A histological diagnosis of lymphocytic myocarditis was made. Acute myocarditis is a rare but potentially fatal complication of the influenza vaccination.
Keywords: cardiopulmonary arrest; influenza; myocarditis; vaccination.