tetano
Editor, Senior Moderator
Br J Haematol
. 2020 Aug 3.
doi: 10.1111/bjh.17060. Online ahead of print.
Abnormal concentration of porphyrins in serum from COVID-19 patients
Itxaso San Juan[SUP] 1 [/SUP], Chiara Bruzzone[SUP] 1 [/SUP], Maider Bizkarguenaga[SUP] 1 [/SUP], Ganeko Bernardo-Seisdedos[SUP] 2 [/SUP], Ana La?n[SUP] 1 [/SUP], Rub?n Gil-Redondo[SUP] 1 [/SUP], Tammo Diercks[SUP] 3 [/SUP], Jon Gil-Mart?nez[SUP] 1 [/SUP], Pedro Urquiza[SUP] 1 [/SUP], Eunate Arana[SUP] 4 [/SUP], Marisa Seco[SUP] 5 [/SUP], Aitor Garc?a de Vicu?a[SUP] 4 [/SUP], Nieves Embade[SUP] 1 [/SUP], Jos? M Mato[SUP] 1 6 [/SUP], Oscar Millet[SUP] 1 2 [/SUP]
Affiliations
Abstract
COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is not only a lung disease but rather a systemic syndrome where blood alterations may play a key role (1). Severe cases show a marked variation in the red blood cell distribution width (2), which agrees well with reduced erythrocyte turnover and would function as a compensatory mechanism to maintain the circulating red blood cell and oxygen levels (3).
Keywords: COVID-19; Porphyrin; heme pathway; pneumonia; serum analysis.
. 2020 Aug 3.
doi: 10.1111/bjh.17060. Online ahead of print.
Abnormal concentration of porphyrins in serum from COVID-19 patients
Itxaso San Juan[SUP] 1 [/SUP], Chiara Bruzzone[SUP] 1 [/SUP], Maider Bizkarguenaga[SUP] 1 [/SUP], Ganeko Bernardo-Seisdedos[SUP] 2 [/SUP], Ana La?n[SUP] 1 [/SUP], Rub?n Gil-Redondo[SUP] 1 [/SUP], Tammo Diercks[SUP] 3 [/SUP], Jon Gil-Mart?nez[SUP] 1 [/SUP], Pedro Urquiza[SUP] 1 [/SUP], Eunate Arana[SUP] 4 [/SUP], Marisa Seco[SUP] 5 [/SUP], Aitor Garc?a de Vicu?a[SUP] 4 [/SUP], Nieves Embade[SUP] 1 [/SUP], Jos? M Mato[SUP] 1 6 [/SUP], Oscar Millet[SUP] 1 2 [/SUP]
Affiliations
- PMID: 32745239
- DOI: 10.1111/bjh.17060
Abstract
COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is not only a lung disease but rather a systemic syndrome where blood alterations may play a key role (1). Severe cases show a marked variation in the red blood cell distribution width (2), which agrees well with reduced erythrocyte turnover and would function as a compensatory mechanism to maintain the circulating red blood cell and oxygen levels (3).
Keywords: COVID-19; Porphyrin; heme pathway; pneumonia; serum analysis.