tetano
Editor, Senior Moderator
Br J Dermatol
. 2021 Jul 14.
doi: 10.1111/bjd.20647. Online ahead of print.
Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic
C Cassius[SUP] 1 2 [/SUP], M Merandet[SUP] 2 [/SUP], L Frumholtz[SUP] 1 [/SUP], D Bergerat[SUP] 2 [/SUP], A Samri[SUP] 3 [/SUP], C Grolleau[SUP] 1 2 [/SUP], L Grzelak[SUP] 4 [/SUP], O Schwartz[SUP] 4 [/SUP], N Yatim[SUP] 1 5 [/SUP], P Moghadam[SUP] 1 [/SUP], L Jaume[SUP] 1 [/SUP], M Bagot[SUP] 1 2 [/SUP], J Legoff[SUP] 6 7 [/SUP], C Delaugerre[SUP] 6 [/SUP], J-D Bouaziz[SUP] 1 2 [/SUP], H Le Buanec[SUP] 2 [/SUP], Saint-Louis CORE (COvid Research)
Affiliations
Abstract
A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic [SUP]1[/SUP] . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy [SUP]2[/SUP] which was further questioned [SUP]3[/SUP] . An indirect link was highlighted with high prevalence of seropositivity in CLL patients compared to general population [SUP]4[/SUP] .
. 2021 Jul 14.
doi: 10.1111/bjd.20647. Online ahead of print.
Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic
C Cassius[SUP] 1 2 [/SUP], M Merandet[SUP] 2 [/SUP], L Frumholtz[SUP] 1 [/SUP], D Bergerat[SUP] 2 [/SUP], A Samri[SUP] 3 [/SUP], C Grolleau[SUP] 1 2 [/SUP], L Grzelak[SUP] 4 [/SUP], O Schwartz[SUP] 4 [/SUP], N Yatim[SUP] 1 5 [/SUP], P Moghadam[SUP] 1 [/SUP], L Jaume[SUP] 1 [/SUP], M Bagot[SUP] 1 2 [/SUP], J Legoff[SUP] 6 7 [/SUP], C Delaugerre[SUP] 6 [/SUP], J-D Bouaziz[SUP] 1 2 [/SUP], H Le Buanec[SUP] 2 [/SUP], Saint-Louis CORE (COvid Research)
Affiliations
- PMID: 34258762
- DOI: 10.1111/bjd.20647
Abstract
A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic [SUP]1[/SUP] . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy [SUP]2[/SUP] which was further questioned [SUP]3[/SUP] . An indirect link was highlighted with high prevalence of seropositivity in CLL patients compared to general population [SUP]4[/SUP] .