tetano
Editor, Senior Moderator
BMC Infect Dis
. 2020 Dec 9;20(1):935.
doi: 10.1186/s12879-020-05680-6.
The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China
Yanzi Li[SUP] 1 [/SUP], Hongxia Li[SUP] 1 [/SUP], Jianfeng Han[SUP] 2 [/SUP], Lin Yang[SUP] 3 4 [/SUP]
Affiliations
Abstract
Background: This study aims to investigate the comparative clinical characteristics of Covid-19 and non-Covid-19 patients.
Methods: Fifteen Covid-19 and 93 non-Covid-19 patients were included in RNA testing. All epidemiological and clinical data were collected and analyzed, and then comparative results were carried out.
Results: Covid-19 patients were older (46.40 ? 18.21 years vs 34.43 ? 18.80 years) and had a higher body weight (70.27 ? 10.67 kg vs 60.54 ? 12.33 kg, P < 0.05). The main symptoms that were similar between Covid-19 and non-Covid-19 patients, and Covid-19 patients showed a lower incidence of sputum production (6.67% vs 45.16%, P < 0.01) and a lower white-cell count (4.83 ? 10[SUP]9[/SUP]/L vs 7.43 ? 10[SUP]9[/SUP]/L) and lymphocyte count (0.90 ? 10[SUP]9[/SUP]/L vs 1.57 ? 10[SUP]9[/SUP]/L, P < 0.01). Although there were no differences, C-reactive protein and interleukin-6 were elevated in Covid-19 patients. The sensitivity and negative predictive value of CT images were 0.87 and 0.97, respectively. Covid-19 patients showed a higher contact history of Wuhan residents (80% vs 30.11%) and higher familial clustering (53.33% vs 8.60%, P < 0.001). Covid-19 patients showed a higher major adverse events (ARDS, 13.33%; death, 6.67%; P < 0.05).
Conclusion: Our results suggested that Covid-19patients had a significant history of exposure and familial clustering and a higher rate of severe status; biochemical indicators showed lymphocyte depletion.
. 2020 Dec 9;20(1):935.
doi: 10.1186/s12879-020-05680-6.
The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China
Yanzi Li[SUP] 1 [/SUP], Hongxia Li[SUP] 1 [/SUP], Jianfeng Han[SUP] 2 [/SUP], Lin Yang[SUP] 3 4 [/SUP]
Affiliations
- PMID: 33297990
- DOI: 10.1186/s12879-020-05680-6
Abstract
Background: This study aims to investigate the comparative clinical characteristics of Covid-19 and non-Covid-19 patients.
Methods: Fifteen Covid-19 and 93 non-Covid-19 patients were included in RNA testing. All epidemiological and clinical data were collected and analyzed, and then comparative results were carried out.
Results: Covid-19 patients were older (46.40 ? 18.21 years vs 34.43 ? 18.80 years) and had a higher body weight (70.27 ? 10.67 kg vs 60.54 ? 12.33 kg, P < 0.05). The main symptoms that were similar between Covid-19 and non-Covid-19 patients, and Covid-19 patients showed a lower incidence of sputum production (6.67% vs 45.16%, P < 0.01) and a lower white-cell count (4.83 ? 10[SUP]9[/SUP]/L vs 7.43 ? 10[SUP]9[/SUP]/L) and lymphocyte count (0.90 ? 10[SUP]9[/SUP]/L vs 1.57 ? 10[SUP]9[/SUP]/L, P < 0.01). Although there were no differences, C-reactive protein and interleukin-6 were elevated in Covid-19 patients. The sensitivity and negative predictive value of CT images were 0.87 and 0.97, respectively. Covid-19 patients showed a higher contact history of Wuhan residents (80% vs 30.11%) and higher familial clustering (53.33% vs 8.60%, P < 0.001). Covid-19 patients showed a higher major adverse events (ARDS, 13.33%; death, 6.67%; P < 0.05).
Conclusion: Our results suggested that Covid-19patients had a significant history of exposure and familial clustering and a higher rate of severe status; biochemical indicators showed lymphocyte depletion.