tetano
Editor, Senior Moderator
BMC Infect Dis
. 2021 Feb 8;21(1):155.
doi: 10.1186/s12879-021-05825-1.
Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province
Wen Wang[SUP] #[/SUP][SUP] 1 [/SUP], Lei Chen[SUP] #[/SUP][SUP] 2 [/SUP], Qiao He[SUP] 1 [/SUP], Mingqi Wang[SUP] 1 [/SUP], Mei Liu[SUP] 1 [/SUP], Taibing Deng[SUP] 3 [/SUP], Xiaoju Deng[SUP] 4 [/SUP], Jianrong Yang[SUP] 5 [/SUP], Ou Jiang[SUP] 6 [/SUP], Rongmei Li[SUP] 7 8 [/SUP], Bo Long[SUP] 9 [/SUP], Gang Mai[SUP] 10 [/SUP], Wenhui Huan[SUP] 11 [/SUP], Wenquan Li[SUP] 12 [/SUP], Xin Jiang[SUP] 13 [/SUP], Zeqiang Wen[SUP] 14 [/SUP], Yongjun Chen[SUP] 15 [/SUP], Wanzhi Fu[SUP] 16 [/SUP], Zhiling Long[SUP] 17 [/SUP], Fanxin Zeng[SUP] 18 [/SUP], Yan Chen[SUP] 19 [/SUP], Yihua Du[SUP] 20 [/SUP], Juan Tang[SUP] 21 [/SUP], Xin Sun[SUP] #[/SUP][SUP] 22 [/SUP], Weimin Li[SUP] #[/SUP][SUP] 23 [/SUP]
Affiliations
Abstract
Background: The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients.
Methods: Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared.
Results: Of the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70?7%), fever (70?5%) and sputum (33?3%), and the most common chest CT patterns were patchy or stripes shadowing (78?0%); throughout the course of disease, 19?0% had no fever, and 12?4% had no radiologic abnormality; twelve (8?2%) received mechanical ventilation, four (2?7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62?5% vs 26?2%, P = 0?001), to present with cough (92?0% vs 66?4%, P = 0?02), sputum (60?0% vs 27?9%, P = 0?004) and shortness of breath (40?0% vs 8?2%, P < 0?0001), and to have more frequent lymphopenia (79?2% vs 43?7%, P = 0?003) and eosinopenia (84?2% vs 57?0%, P = 0?046).
Conclusions: The symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.
Keywords: COVID-19; Clinical characteristics; Novel coronavirus.
. 2021 Feb 8;21(1):155.
doi: 10.1186/s12879-021-05825-1.
Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province
Wen Wang[SUP] #[/SUP][SUP] 1 [/SUP], Lei Chen[SUP] #[/SUP][SUP] 2 [/SUP], Qiao He[SUP] 1 [/SUP], Mingqi Wang[SUP] 1 [/SUP], Mei Liu[SUP] 1 [/SUP], Taibing Deng[SUP] 3 [/SUP], Xiaoju Deng[SUP] 4 [/SUP], Jianrong Yang[SUP] 5 [/SUP], Ou Jiang[SUP] 6 [/SUP], Rongmei Li[SUP] 7 8 [/SUP], Bo Long[SUP] 9 [/SUP], Gang Mai[SUP] 10 [/SUP], Wenhui Huan[SUP] 11 [/SUP], Wenquan Li[SUP] 12 [/SUP], Xin Jiang[SUP] 13 [/SUP], Zeqiang Wen[SUP] 14 [/SUP], Yongjun Chen[SUP] 15 [/SUP], Wanzhi Fu[SUP] 16 [/SUP], Zhiling Long[SUP] 17 [/SUP], Fanxin Zeng[SUP] 18 [/SUP], Yan Chen[SUP] 19 [/SUP], Yihua Du[SUP] 20 [/SUP], Juan Tang[SUP] 21 [/SUP], Xin Sun[SUP] #[/SUP][SUP] 22 [/SUP], Weimin Li[SUP] #[/SUP][SUP] 23 [/SUP]
Affiliations
- PMID: 33557777
- DOI: 10.1186/s12879-021-05825-1
Abstract
Background: The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients.
Methods: Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared.
Results: Of the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70?7%), fever (70?5%) and sputum (33?3%), and the most common chest CT patterns were patchy or stripes shadowing (78?0%); throughout the course of disease, 19?0% had no fever, and 12?4% had no radiologic abnormality; twelve (8?2%) received mechanical ventilation, four (2?7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62?5% vs 26?2%, P = 0?001), to present with cough (92?0% vs 66?4%, P = 0?02), sputum (60?0% vs 27?9%, P = 0?004) and shortness of breath (40?0% vs 8?2%, P < 0?0001), and to have more frequent lymphopenia (79?2% vs 43?7%, P = 0?003) and eosinopenia (84?2% vs 57?0%, P = 0?046).
Conclusions: The symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.
Keywords: COVID-19; Clinical characteristics; Novel coronavirus.