tetano
Editor, Senior Moderator
Biomed Rep
. 2022 Feb;16(2):10.
doi: 10.3892/br.2021.1493. Epub 2021 Dec 15.
Post-infectious ST elevation myocardial infarction following a COVID-19 infection: A case report
Manuela Ceccarelli[SUP] 1 [/SUP], Andrea Marino[SUP] 1 [/SUP], Federica Cosentino[SUP] 1 2 [/SUP], Vittoria Moscatt[SUP] 1 2 [/SUP], Benedetto Maurizio Celesia[SUP] 1 [/SUP], Maria Gussio[SUP] 1 [/SUP], Roberto Bruno[SUP] 1 [/SUP], Emmanuele Venanzi Rullo[SUP] 2 [/SUP], Giuseppe Nunnari[SUP] 2 [/SUP], Bruno Santi Cacopardo[SUP] 1 [/SUP]
Affiliations
Abstract
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has been shown to increase the risk of thrombotic events due to a hypercoagulable state caused by several factors. The case of a 59-year-old woman affected by hypertension and metabolic disorders, treated for a COVID-19 infection who developed cardiac symptoms during the first days of hospitalization is reported. Electrocardiogram analysis and cardiac-ultrasound confirmed ST-segment elevation myocardial infarction (STEMI) diagnosis, thus the patient underwent percutaneous coronary intervention, which was successful. This case highlights a possible association between respiratory infection, particularly SARS-CoV-2 infection, and cardiovascular events, in particular Acute Coronary Syndrome. The association between these phenomena seems related to a range of factors, including a proinflammatory state and the hypoxemia. Moreover, the association amongst SARS-CoV-2 and cardiovascular diseases may be also linked to long-term sequelae. Thus, further studies are required to better understand the multifaceted and severe complications of this disease.
Keywords: COVID-19; ST-segment elevation myocardial infarction; Severe Acute Respiratory Syndrome-Coronavirus-2; post-infectious sequelae.
. 2022 Feb;16(2):10.
doi: 10.3892/br.2021.1493. Epub 2021 Dec 15.
Post-infectious ST elevation myocardial infarction following a COVID-19 infection: A case report
Manuela Ceccarelli[SUP] 1 [/SUP], Andrea Marino[SUP] 1 [/SUP], Federica Cosentino[SUP] 1 2 [/SUP], Vittoria Moscatt[SUP] 1 2 [/SUP], Benedetto Maurizio Celesia[SUP] 1 [/SUP], Maria Gussio[SUP] 1 [/SUP], Roberto Bruno[SUP] 1 [/SUP], Emmanuele Venanzi Rullo[SUP] 2 [/SUP], Giuseppe Nunnari[SUP] 2 [/SUP], Bruno Santi Cacopardo[SUP] 1 [/SUP]
Affiliations
- PMID: 34987794
- PMCID: PMC8719316
- DOI: 10.3892/br.2021.1493
Abstract
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has been shown to increase the risk of thrombotic events due to a hypercoagulable state caused by several factors. The case of a 59-year-old woman affected by hypertension and metabolic disorders, treated for a COVID-19 infection who developed cardiac symptoms during the first days of hospitalization is reported. Electrocardiogram analysis and cardiac-ultrasound confirmed ST-segment elevation myocardial infarction (STEMI) diagnosis, thus the patient underwent percutaneous coronary intervention, which was successful. This case highlights a possible association between respiratory infection, particularly SARS-CoV-2 infection, and cardiovascular events, in particular Acute Coronary Syndrome. The association between these phenomena seems related to a range of factors, including a proinflammatory state and the hypoxemia. Moreover, the association amongst SARS-CoV-2 and cardiovascular diseases may be also linked to long-term sequelae. Thus, further studies are required to better understand the multifaceted and severe complications of this disease.
Keywords: COVID-19; ST-segment elevation myocardial infarction; Severe Acute Respiratory Syndrome-Coronavirus-2; post-infectious sequelae.