tetano
Editor, Senior Moderator
Infect Genet Evol. 2015 Feb 9. pii: S1567-1348(15)00018-0. doi: 10.1016/j.meegid.2015.01.014. [Epub ahead of print]
[h=1]Beagle dogs have low susceptibility to BJ94-like H9N2 avian influenza virus.[/h] Zhou P[SUP]1[/SUP], Wang L[SUP]1[/SUP], Huang S[SUP]1[/SUP], Fu C[SUP]1[/SUP], He H[SUP]1[/SUP], Hong M[SUP]1[/SUP], Su S[SUP]1[/SUP], Li S[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In China, dogs are considered significant intermediate hosts of influenza viruses and have been reported to be infected with H9N2; additionally, a reassortant H9N2 virus has been isolated in dogs. Currently, there are three different lineages of H9N2, including BJ94-like, G1-like, and Y439-like lineages; BJ94-like H9N2 has been circulating in various types of poultry in southern China. Additionally, a number of studies have reported that H9N2 evolves rapidly and is frequently reassorted with H5N1, H7N9, or H10N8 to generate novel reassortants, which is significant for poultry and humans. In this study, two groups of beagles were inoculated either intranasally or intratracheally with the BJ94-like H9N2 virus. However, only four of the seven beagles in the intranasal group and five of the seven beagles in the intratracheal group displayed a mild fever; similarly, only two of the five beagles in the intranasal group and three of the five beagles in the intratracheal group underwent seroconversion. However, no viruses were detected from nasal swabs or rectal swabs or in the lungs of any of the inoculated beagles. Our results demonstrated that beagles have low susceptibility to the BJ94-like H9N2 avian influenza virus, which is the main virus circulating in southern China, indicating that the BJ94-like H9N2 virus does not currently threaten the health of dogs.
Copyright ? 2015 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] DOGS; H9N2; Low susceptible
PMID: 25675837 [PubMed - as supplied by publisher]
[h=1]Beagle dogs have low susceptibility to BJ94-like H9N2 avian influenza virus.[/h] Zhou P[SUP]1[/SUP], Wang L[SUP]1[/SUP], Huang S[SUP]1[/SUP], Fu C[SUP]1[/SUP], He H[SUP]1[/SUP], Hong M[SUP]1[/SUP], Su S[SUP]1[/SUP], Li S[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In China, dogs are considered significant intermediate hosts of influenza viruses and have been reported to be infected with H9N2; additionally, a reassortant H9N2 virus has been isolated in dogs. Currently, there are three different lineages of H9N2, including BJ94-like, G1-like, and Y439-like lineages; BJ94-like H9N2 has been circulating in various types of poultry in southern China. Additionally, a number of studies have reported that H9N2 evolves rapidly and is frequently reassorted with H5N1, H7N9, or H10N8 to generate novel reassortants, which is significant for poultry and humans. In this study, two groups of beagles were inoculated either intranasally or intratracheally with the BJ94-like H9N2 virus. However, only four of the seven beagles in the intranasal group and five of the seven beagles in the intratracheal group displayed a mild fever; similarly, only two of the five beagles in the intranasal group and three of the five beagles in the intratracheal group underwent seroconversion. However, no viruses were detected from nasal swabs or rectal swabs or in the lungs of any of the inoculated beagles. Our results demonstrated that beagles have low susceptibility to the BJ94-like H9N2 avian influenza virus, which is the main virus circulating in southern China, indicating that the BJ94-like H9N2 virus does not currently threaten the health of dogs.
Copyright ? 2015 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] DOGS; H9N2; Low susceptible
PMID: 25675837 [PubMed - as supplied by publisher]