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ASAIO J . FDA Emergency Use Authorization-Approved Novel Coronavirus Disease 2019, Pressure-Regulated, Mechanical Ventilator Splitter That Enables

tetano

Editor, Senior Moderator
ASAIO J


. 2022 Jun 3.
doi: 10.1097/MAT.0000000000001756. Online ahead of print.
FDA Emergency Use Authorization-Approved Novel Coronavirus Disease 2019, Pressure-Regulated, Mechanical Ventilator Splitter That Enables Differential Compliance Multiplexing


Michael J Paulsen[SUP] 1 [/SUP], Yuanjia Zhu[SUP] 1 2 [/SUP], Matthew H Park[SUP] 1 3 [/SUP], Annabel M Imbrie-Moore[SUP] 1 3 [/SUP], Sam Baker[SUP] 4 [/SUP], David Walter Edmonston[SUP] 5 [/SUP], Tyler Dawson[SUP] 5 [/SUP], Evan Ly[SUP] 5 [/SUP], Shannon Martin Bell[SUP] 5 [/SUP], Nick A Tran[SUP] 1 [/SUP], Jinsuh Jung[SUP] 1 [/SUP], Jordan Cedarleaf-Pavy[SUP] 5 [/SUP], K R Sridhar[SUP] 5 [/SUP], Venkat Venkataraman[SUP] 5 [/SUP], Y Joseph Woo[SUP] 1 2 [/SUP]



Affiliations

Abstract

Infection with the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may cause viral pneumonia and acute respiratory distress syndrome (ARDS). Treatment of ARDS often requires mechanical ventilation and may take weeks for resolution. In areas with a large outbreaks, there may be shortages of ventilators available. While rudimentary methods for ventilator splitting have been described, given the range of independent ventilatory settings required for each patient, this solution is suboptimal. Here, we describe a device that can split a ventilator among up to four patients while allowing for individualized settings. The device has been validated in vitro and in vivo.
 
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