tetano
Editor, Senior Moderator
Arch Virol
. 2022 Oct 21.
doi: 10.1007/s00705-022-05615-3. Online ahead of print.
SARS-CoV-2 and seasonal influenza: similarities and disparities
Halima Dabaja-Younis[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Eyal Fuchs[SUP] #[/SUP][SUP] 4 [/SUP], Nadeem Shorbaji[SUP] 5 [/SUP], Tal Appel[SUP] 6 [/SUP], Noah Carmon[SUP] 7 [/SUP], Yael Shachor-Meyouhas[SUP] 8 7 [/SUP], Manfred S Green[SUP] 9 [/SUP], Khetam Hussein[SUP] 10 7 [/SUP]
Affiliations
Abstract
This report describes the differences in disease severity and clinical presentation between hospitalized patients with coronavirus disease 2019 (COVID-19) and others with seasonal influenza. A total of 136 influenza and 152 COVID-19 patients were included. Patients with influenza more frequently had dyspnea (p = 0.004), hypoxemia (p < 0.001), underlying diseases (p = 0.046), and elevated liver enzymes (p = 0.028). In contrast, patients with COVID-19 were overweight (p < 0.001), lymphopenic (p < 0.001), had elevated CRP (p = 0.011), and radiological abnormalities (p < 0.001). Patients with influenza were more severely ill on admission (NEWS > 5) (p < 0.001). However, length of hospital stay, ventilatory support, and 30-day-mortality were similar. Despite differences in clinical presentation and disease severity between influenza and COVID-19 patients, both groups had similar clinical outcomes.
. 2022 Oct 21.
doi: 10.1007/s00705-022-05615-3. Online ahead of print.
SARS-CoV-2 and seasonal influenza: similarities and disparities
Halima Dabaja-Younis[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Eyal Fuchs[SUP] #[/SUP][SUP] 4 [/SUP], Nadeem Shorbaji[SUP] 5 [/SUP], Tal Appel[SUP] 6 [/SUP], Noah Carmon[SUP] 7 [/SUP], Yael Shachor-Meyouhas[SUP] 8 7 [/SUP], Manfred S Green[SUP] 9 [/SUP], Khetam Hussein[SUP] 10 7 [/SUP]
Affiliations
- PMID: 36269417
- DOI: 10.1007/s00705-022-05615-3
Abstract
This report describes the differences in disease severity and clinical presentation between hospitalized patients with coronavirus disease 2019 (COVID-19) and others with seasonal influenza. A total of 136 influenza and 152 COVID-19 patients were included. Patients with influenza more frequently had dyspnea (p = 0.004), hypoxemia (p < 0.001), underlying diseases (p = 0.046), and elevated liver enzymes (p = 0.028). In contrast, patients with COVID-19 were overweight (p < 0.001), lymphopenic (p < 0.001), had elevated CRP (p = 0.011), and radiological abnormalities (p < 0.001). Patients with influenza were more severely ill on admission (NEWS > 5) (p < 0.001). However, length of hospital stay, ventilatory support, and 30-day-mortality were similar. Despite differences in clinical presentation and disease severity between influenza and COVID-19 patients, both groups had similar clinical outcomes.