tetano
Editor, Senior Moderator
Chem Commun (Camb). 2014 Oct 30. [Epub ahead of print]
Aptamer-based biosensors for the rapid visual detection of flu viruses.
Le TT1, Adamiak B, Benton DJ, Johnson CJ, Sharma S, Fenton R, McCauley JW, Iqbal M, Cass AE.
Author information
Abstract
RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 ? 108 viral particles.
PMID:
25354585
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25354585
Aptamer-based biosensors for the rapid visual detection of flu viruses.
Le TT1, Adamiak B, Benton DJ, Johnson CJ, Sharma S, Fenton R, McCauley JW, Iqbal M, Cass AE.
Author information
Abstract
RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 ? 108 viral particles.
PMID:
25354585
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25354585