tetano
Editor, Senior Moderator
Bioorg Med Chem Lett. 2015 May 31. pii: S0960-894X(15)00555-7. doi: 10.1016/j.bmcl.2015.05.081. [Epub ahead of print]
[h=1]Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii.[/h] Hwang BS[SUP]1[/SUP], Lee IK[SUP]1[/SUP], Choi HJ[SUP]2[/SUP], Yun BS[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Five polyphenols were isolated from the ethanolic extract of the fruiting bodies of Phellinus baumii. These compounds were identified by various spectroscopic methods as hispidin, hypholomine B, inoscavin A, davallialactone, and phelligridin D. All compounds inhibited noncompetitively H1N1, H5N1, and H3N2 neuraminidase activity and reduced the amount of virally-induced cytopathic effect (CPE) according to an MDCK cell-based assay.
Copyright ? 2015 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Anti-influenza; Cytopathic effect; Neuraminidase inhibition; Phellinus baumii; Polyphenol
PMID: 26077494 [PubMed - as supplied by publisher]
[h=1]Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii.[/h] Hwang BS[SUP]1[/SUP], Lee IK[SUP]1[/SUP], Choi HJ[SUP]2[/SUP], Yun BS[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Five polyphenols were isolated from the ethanolic extract of the fruiting bodies of Phellinus baumii. These compounds were identified by various spectroscopic methods as hispidin, hypholomine B, inoscavin A, davallialactone, and phelligridin D. All compounds inhibited noncompetitively H1N1, H5N1, and H3N2 neuraminidase activity and reduced the amount of virally-induced cytopathic effect (CPE) according to an MDCK cell-based assay.
Copyright ? 2015 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Anti-influenza; Cytopathic effect; Neuraminidase inhibition; Phellinus baumii; Polyphenol
PMID: 26077494 [PubMed - as supplied by publisher]