tetano
Editor, Senior Moderator
Ann Lab Med
. 2020 Nov;40(6):439-447.
doi: 10.3343/alm.2020.40.6.439. Epub 2020 Nov 1.
COVID-19 Molecular Testing in Korea: Practical Essentials and Answers From Experts Based on Experiences of Emergency Use Authorization Assays
Heungsup Sung[SUP] 1 [/SUP], Kyoung Ho Roh[SUP] 2 [/SUP], Ki Ho Hong[SUP] 3 [/SUP], Moon-Woo Seong[SUP] 4 [/SUP], Namhee Ryoo[SUP] 5 [/SUP], Hyun Soo Kim[SUP] 6 [/SUP], Jaehyeon Lee[SUP] 7 [/SUP], So Yeon Kim[SUP] 8 [/SUP], Sookwon Yoo[SUP] 9 [/SUP], Mi-Na Kim[SUP] 1 [/SUP], Myung Guk Han[SUP] 10 [/SUP], Sang Won Lee[SUP] 10 [/SUP], Hyukmin Lee[SUP] 11 [/SUP], Cheon Kwon Yoo[SUP] 10 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early detection of COVID-19 and immediate isolation of infected patients from the naive population are important to prevent further pandemic spread of the infection. Real-time reverse transcription (RT)-PCR to detect SARS-CoV-2 RNA is currently the most reliable diagnostic method for confirming COVID-19 worldwide. Guidelines for clinical laboratories on the COVID-19 diagnosis have been recently published by Korean Society for Laboratory Medicine and the Korea Centers for Disease Control and Prevention. However, these formal guidelines do not address common practical laboratory issues related to COVID-19 real-time RT-PCR testing and their solutions. Therefore, this guideline is intended as a practical and technical supplement to the "Guidelines for Laboratory Diagnosis of COVID-19 in Korea".
Keywords: Coronavirus disease 2019; Guidelines; Korea; Laboratory diagnosis; Real-time RT-PCR.
. 2020 Nov;40(6):439-447.
doi: 10.3343/alm.2020.40.6.439. Epub 2020 Nov 1.
COVID-19 Molecular Testing in Korea: Practical Essentials and Answers From Experts Based on Experiences of Emergency Use Authorization Assays
Heungsup Sung[SUP] 1 [/SUP], Kyoung Ho Roh[SUP] 2 [/SUP], Ki Ho Hong[SUP] 3 [/SUP], Moon-Woo Seong[SUP] 4 [/SUP], Namhee Ryoo[SUP] 5 [/SUP], Hyun Soo Kim[SUP] 6 [/SUP], Jaehyeon Lee[SUP] 7 [/SUP], So Yeon Kim[SUP] 8 [/SUP], Sookwon Yoo[SUP] 9 [/SUP], Mi-Na Kim[SUP] 1 [/SUP], Myung Guk Han[SUP] 10 [/SUP], Sang Won Lee[SUP] 10 [/SUP], Hyukmin Lee[SUP] 11 [/SUP], Cheon Kwon Yoo[SUP] 10 [/SUP]
Affiliations
- PMID: 32539299
- DOI: 10.3343/alm.2020.40.6.439
Abstract
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early detection of COVID-19 and immediate isolation of infected patients from the naive population are important to prevent further pandemic spread of the infection. Real-time reverse transcription (RT)-PCR to detect SARS-CoV-2 RNA is currently the most reliable diagnostic method for confirming COVID-19 worldwide. Guidelines for clinical laboratories on the COVID-19 diagnosis have been recently published by Korean Society for Laboratory Medicine and the Korea Centers for Disease Control and Prevention. However, these formal guidelines do not address common practical laboratory issues related to COVID-19 real-time RT-PCR testing and their solutions. Therefore, this guideline is intended as a practical and technical supplement to the "Guidelines for Laboratory Diagnosis of COVID-19 in Korea".
Keywords: Coronavirus disease 2019; Guidelines; Korea; Laboratory diagnosis; Real-time RT-PCR.