tetano
Editor, Senior Moderator
Curr Opin Virol. 2015 Jun 27;13:101-108. doi: 10.1016/j.coviro.2015.06.002. [Epub ahead of print]
[h=1]Animal models for influenza virus transmission studies: a historical perspective.[/h] Bouvier NM[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Animal models are used to simulate, under experimental conditions, the complex interactions among host, virus, and environment that affect the person-to-person spread of influenza viruses. The three species that have been most frequently employed, both past and present, as influenza virus transmission models-ferrets, mice, and guinea pigs-have each provided unique insights into the factors governing the efficiency with which these viruses pass from an infected host to a susceptible one. This review will highlight a few of these noteworthy discoveries, with a particular focus on the historical contexts in which each model was developed and the advantages and disadvantages of each species with regard to the study of influenza virus transmission among mammals.
Copyright ? 2015 Elsevier B.V. All rights reserved.
PMID: 26126082 [PubMed - as supplied by publisher]
[h=1]Animal models for influenza virus transmission studies: a historical perspective.[/h] Bouvier NM[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Animal models are used to simulate, under experimental conditions, the complex interactions among host, virus, and environment that affect the person-to-person spread of influenza viruses. The three species that have been most frequently employed, both past and present, as influenza virus transmission models-ferrets, mice, and guinea pigs-have each provided unique insights into the factors governing the efficiency with which these viruses pass from an infected host to a susceptible one. This review will highlight a few of these noteworthy discoveries, with a particular focus on the historical contexts in which each model was developed and the advantages and disadvantages of each species with regard to the study of influenza virus transmission among mammals.
Copyright ? 2015 Elsevier B.V. All rights reserved.
PMID: 26126082 [PubMed - as supplied by publisher]