tetano
Editor, Senior Moderator
Angiology
. 2021 Jul 28;33197211028760.
doi: 10.1177/00033197211028760. Online ahead of print.
Angiographic and Clinical Profile of Patients With COVID-19 Referred for Coronary Angiography During SARS-CoV-2 Outbreak: Results From a Collaborative, European, Multicenter Registry
J M Montero-Cabezas[SUP] 1 [/SUP], J G Córdoba-Soriano[SUP] 2 [/SUP], F Díez-Delhoyo[SUP] 3 [/SUP], J Abellán-Huerta[SUP] 4 [/SUP], H Girgis[SUP] 5 [/SUP], J C Rama-Merchán[SUP] 6 [/SUP], S García-Blas[SUP] 7 [/SUP], J B van Rees[SUP] 8 [/SUP], J van Ramshorst[SUP] 9 [/SUP], A Jurado-Román[SUP] 10 [/SUP]
Affiliations
Abstract
Data regarding angiographic characteristics, clinical profile, and inhospital outcomes of patients with coronavirus disease 2019 (COVID-19) referred for coronary angiography (CAG) are scarce. This is an observational study analyzing confirmed patients with COVID-19 referred for CAG from 10 European centers. We included 57 patients (mean age: 66 ± 15 years, 82% male) , of whom 18% had previous myocardial infarction (MI) and 29% had renal insufficiency and chronic pulmonary disease. ST-segment elevation myocardial infarction (STEMI) was the most frequent indication for CAG (58%). Coronavirus disease 2019 was confirmed after CAG in 86% and classified as mild in 49%, with 21% fully asymptomatic. A culprit lesion was identified in 79% and high thrombus burden in 42%; 7% had stent thrombosis. At 40 days follow-up, 16 (28%) patients experienced a major adverse cardiovascular event (MACE): 12 deaths (92% noncardiac), 1 MI, 2 stent thrombosis, and 1 stroke. In an European multicenter registry, patients with confirmed COVID-19 infection referred for CAG during the first wave of the severe acute respiratory syndrome coronavirus 2 pandemic presented mostly with STEMI and were predominantly males with comorbidities. Severity of COVID-19 was in general noncritical and 21% were asymptomatic at the time of CAG. Culprit coronary lesions with high thrombus burden were frequently identified, with a rate of stent thrombosis of 7%. The incidence of MACE at 40 days was high (28%), mostly due to noncardiac death.
Keywords: MACE; SYNTAX score; acute coronary syndrome; coronary angiography; coronary artery disease; thrombosis.
. 2021 Jul 28;33197211028760.
doi: 10.1177/00033197211028760. Online ahead of print.
Angiographic and Clinical Profile of Patients With COVID-19 Referred for Coronary Angiography During SARS-CoV-2 Outbreak: Results From a Collaborative, European, Multicenter Registry
J M Montero-Cabezas[SUP] 1 [/SUP], J G Córdoba-Soriano[SUP] 2 [/SUP], F Díez-Delhoyo[SUP] 3 [/SUP], J Abellán-Huerta[SUP] 4 [/SUP], H Girgis[SUP] 5 [/SUP], J C Rama-Merchán[SUP] 6 [/SUP], S García-Blas[SUP] 7 [/SUP], J B van Rees[SUP] 8 [/SUP], J van Ramshorst[SUP] 9 [/SUP], A Jurado-Román[SUP] 10 [/SUP]
Affiliations
- PMID: 34318686
- DOI: 10.1177/00033197211028760
Abstract
Data regarding angiographic characteristics, clinical profile, and inhospital outcomes of patients with coronavirus disease 2019 (COVID-19) referred for coronary angiography (CAG) are scarce. This is an observational study analyzing confirmed patients with COVID-19 referred for CAG from 10 European centers. We included 57 patients (mean age: 66 ± 15 years, 82% male) , of whom 18% had previous myocardial infarction (MI) and 29% had renal insufficiency and chronic pulmonary disease. ST-segment elevation myocardial infarction (STEMI) was the most frequent indication for CAG (58%). Coronavirus disease 2019 was confirmed after CAG in 86% and classified as mild in 49%, with 21% fully asymptomatic. A culprit lesion was identified in 79% and high thrombus burden in 42%; 7% had stent thrombosis. At 40 days follow-up, 16 (28%) patients experienced a major adverse cardiovascular event (MACE): 12 deaths (92% noncardiac), 1 MI, 2 stent thrombosis, and 1 stroke. In an European multicenter registry, patients with confirmed COVID-19 infection referred for CAG during the first wave of the severe acute respiratory syndrome coronavirus 2 pandemic presented mostly with STEMI and were predominantly males with comorbidities. Severity of COVID-19 was in general noncritical and 21% were asymptomatic at the time of CAG. Culprit coronary lesions with high thrombus burden were frequently identified, with a rate of stent thrombosis of 7%. The incidence of MACE at 40 days was high (28%), mostly due to noncardiac death.
Keywords: MACE; SYNTAX score; acute coronary syndrome; coronary angiography; coronary artery disease; thrombosis.