tetano
Editor, Senior Moderator
J Clin Virol. 2012 Sep 11. pii: S1386-6532(12)00319-8. doi: 10.1016/j.jcv.2012.08.015. [Epub ahead of print]
Analysis of Vis-NIR spectra changes to measure the inflammatory response in the nasal mucosal region of influenza A and B virus-infected patients.
Sakudo A, Baba K, Ikuta K.
Source
Department of Virology, Center for Infectious Disease Control, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: sakudo@med.u-ryukyu.ac.jp.
Abstract
BACKGROUND:
Human influenza A and B viruses cause severe seasonal respiratory tract infections, especially in infants and young children. Influenza A and B viruses have been reported to produce different symptoms and/or severity in infected patients, although these remain inconclusive.
OBJECTIVES AND STUDY DESIGN:
In this study, non-invasive visible and near-infrared (Vis-NIR) spectroscopy was used for comparative analysis of the inflammatory response to influenza A and B virus infections, by measuring changes in water peak (970nm) spectra collected from patient nasal mucosal regions.
RESULTS:
The results suggested that infection with influenza B virus induced more severe inflammatory responses in the nasal mucosal region than influenza A virus.
CONCLUSIONS:
These are the first data showing different inflammatory responses to influenza A and B viruses at the sites of virus infection.
Copyright ? 2012 Elsevier B.V. All rights reserved.
PMID:
22981622
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22981622
Analysis of Vis-NIR spectra changes to measure the inflammatory response in the nasal mucosal region of influenza A and B virus-infected patients.
Sakudo A, Baba K, Ikuta K.
Source
Department of Virology, Center for Infectious Disease Control, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: sakudo@med.u-ryukyu.ac.jp.
Abstract
BACKGROUND:
Human influenza A and B viruses cause severe seasonal respiratory tract infections, especially in infants and young children. Influenza A and B viruses have been reported to produce different symptoms and/or severity in infected patients, although these remain inconclusive.
OBJECTIVES AND STUDY DESIGN:
In this study, non-invasive visible and near-infrared (Vis-NIR) spectroscopy was used for comparative analysis of the inflammatory response to influenza A and B virus infections, by measuring changes in water peak (970nm) spectra collected from patient nasal mucosal regions.
RESULTS:
The results suggested that infection with influenza B virus induced more severe inflammatory responses in the nasal mucosal region than influenza A virus.
CONCLUSIONS:
These are the first data showing different inflammatory responses to influenza A and B viruses at the sites of virus infection.
Copyright ? 2012 Elsevier B.V. All rights reserved.
PMID:
22981622
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22981622