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Am J Otolaryngol . COVID-19 and Anosmia: A Review Based on Up-To-Date Knowledge

tetano

Editor, Senior Moderator
Am J Otolaryngol


. 2020 Jun 2;41(5):102581.
doi: 10.1016/j.amjoto.2020.102581. Online ahead of print.
COVID-19 and Anosmia: A Review Based on Up-To-Date Knowledge


Xiangming Meng[SUP] 1 [/SUP], Yanzhong Deng[SUP] 2 [/SUP], Zhiyong Dai[SUP] 3 [/SUP], Zhisheng Meng[SUP] 4 [/SUP]



Affiliations

Abstract

The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature.

Keywords: Anosmia; COVID-19; Coronavirus; Olfactory dysfunction; Otolaryngology; SARS-CoV-2; Smell.
 
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