tetano
Editor, Senior Moderator
Am J Ophthalmol Case Rep
. 2020 Dec 13;20:101001.
doi: 10.1016/j.ajoc.2020.101001. eCollection 2020 Dec.
Bilateral optic neuritis with spine demyelination associated with influenza A H1N1 infection
Selvakumar Ambika[SUP] 1 [/SUP], Padma Lakshmi[SUP] 1 [/SUP], Olma Veena Noronha[SUP] 2 [/SUP]
Affiliations
Abstract
Purpose: To report a rare case of optic neuritis with spine demyelination following H1N1 virus infection.
Observation: A 66-year-old female presented with decreased vision in both eyes (left > right) following a recent episode of fever and flu. She was diagnosed as H1N1 infection confirmed by viral antigen analysis of throat swab. On examination, she had a profound vision drop in the left eye with optic disc edema. MRI brain and orbit revealed bilateral optic nerve and frontal dural thickening with a ring-enhancing lesion in the right frontal lobe. MRI spine showed long cord signals at T1-T7 suggestive of demyelination. The patient had a complete recovery of vision and visual fields after intravenous and oral steroids.
Conclusion/importance: Influenza A virus can manifest with a wide range of symptoms including flu-like illness to neurological complications. This case highlights optic neuritis as a presenting feature of H1N1 infection.
Keywords: Demyelination; Disc edema; H1N1; MRI; Optic neuritis; Steroids.
. 2020 Dec 13;20:101001.
doi: 10.1016/j.ajoc.2020.101001. eCollection 2020 Dec.
Bilateral optic neuritis with spine demyelination associated with influenza A H1N1 infection
Selvakumar Ambika[SUP] 1 [/SUP], Padma Lakshmi[SUP] 1 [/SUP], Olma Veena Noronha[SUP] 2 [/SUP]
Affiliations
- PMID: 33364518
- PMCID: PMC7750147
- DOI: 10.1016/j.ajoc.2020.101001
Abstract
Purpose: To report a rare case of optic neuritis with spine demyelination following H1N1 virus infection.
Observation: A 66-year-old female presented with decreased vision in both eyes (left > right) following a recent episode of fever and flu. She was diagnosed as H1N1 infection confirmed by viral antigen analysis of throat swab. On examination, she had a profound vision drop in the left eye with optic disc edema. MRI brain and orbit revealed bilateral optic nerve and frontal dural thickening with a ring-enhancing lesion in the right frontal lobe. MRI spine showed long cord signals at T1-T7 suggestive of demyelination. The patient had a complete recovery of vision and visual fields after intravenous and oral steroids.
Conclusion/importance: Influenza A virus can manifest with a wide range of symptoms including flu-like illness to neurological complications. This case highlights optic neuritis as a presenting feature of H1N1 infection.
Keywords: Demyelination; Disc edema; H1N1; MRI; Optic neuritis; Steroids.