tetano
Editor, Senior Moderator
Am J Obstet Gynecol. 2020 Apr 17. pii: S0002-9378(20)30438-5. doi: 10.1016/j.ajog.2020.04.013. [Epub ahead of print]
COVID19 during pregnancy: a systematic review of reported cases.
Della Gatta AN[SUP]1[/SUP], Rizzo R[SUP]2[/SUP], Pilu G[SUP]2[/SUP], Simonazzi G[SUP]2[/SUP].
Author information
Abstract
OBJECTIVE:
to conduct a systematic review of the outcomes reported for pregnant patients with COVID 19.
DATA SOURCES:
we searched electronically Pubmed, Cinahl, Scopus using combination of keywords "Coronavirus and/ or pregnancy"; "COVID and/or pregnancy"; "COVID disease and/or pregnancy"; "COVID pneumonia and/or pregnancy. There were no restriction of languages in order to collect as much cases as possible.
STUDY ELIGIBILITY CRITERIA:
all pregnant women, with a COVID19 diagnosed with acid nucleic test, with reported data about pregnancy and, in case of delivery, reported outcomes.
STUDY APPRAISAL AND SYNTHESIS METHODS:
all the studies included have been evaluated according the tool for evaluating the methodological quality of case reports and case series described by Murad et al. RESULTS: 6 studies including 51 women were eligible for the systematic review. Three pregnancies were ongoing at the time of the report; of the remaining 48, 46 were delivered with a cesarean section and 2 vaginally; there was 1 stillbirth and 1 neonatal death.
CONCLUSIONS:
although vertical transmission of SARS-Cov2 has been excluded thus far and the outcome for mothers and fetuses has been generally good, the high rate of preterm cesarean delivery is a reason for concern. These interventions were typically elective, and it is reasonable to question whether they were warranted or not. COVID-19 associated with respiratory insufficiency in late pregnancies certainly creates a complex clinical scenario.
Copyright ? 2020 Elsevier Inc. All rights reserved.
KEYWORDS:
COVID19; Coronavirus pneumonia in pregnant women; SARS-CoV-2; Viral pneumonia; cesarean section; fetal death; neonatal outcomes in COVID 19; preterm birth; stillbirth; vertical transmission novel coronavirus
PMID:32311350DOI:10.1016/j.ajog.2020.04.013
COVID19 during pregnancy: a systematic review of reported cases.
Della Gatta AN[SUP]1[/SUP], Rizzo R[SUP]2[/SUP], Pilu G[SUP]2[/SUP], Simonazzi G[SUP]2[/SUP].
Author information
Abstract
OBJECTIVE:
to conduct a systematic review of the outcomes reported for pregnant patients with COVID 19.
DATA SOURCES:
we searched electronically Pubmed, Cinahl, Scopus using combination of keywords "Coronavirus and/ or pregnancy"; "COVID and/or pregnancy"; "COVID disease and/or pregnancy"; "COVID pneumonia and/or pregnancy. There were no restriction of languages in order to collect as much cases as possible.
STUDY ELIGIBILITY CRITERIA:
all pregnant women, with a COVID19 diagnosed with acid nucleic test, with reported data about pregnancy and, in case of delivery, reported outcomes.
STUDY APPRAISAL AND SYNTHESIS METHODS:
all the studies included have been evaluated according the tool for evaluating the methodological quality of case reports and case series described by Murad et al. RESULTS: 6 studies including 51 women were eligible for the systematic review. Three pregnancies were ongoing at the time of the report; of the remaining 48, 46 were delivered with a cesarean section and 2 vaginally; there was 1 stillbirth and 1 neonatal death.
CONCLUSIONS:
although vertical transmission of SARS-Cov2 has been excluded thus far and the outcome for mothers and fetuses has been generally good, the high rate of preterm cesarean delivery is a reason for concern. These interventions were typically elective, and it is reasonable to question whether they were warranted or not. COVID-19 associated with respiratory insufficiency in late pregnancies certainly creates a complex clinical scenario.
Copyright ? 2020 Elsevier Inc. All rights reserved.
KEYWORDS:
COVID19; Coronavirus pneumonia in pregnant women; SARS-CoV-2; Viral pneumonia; cesarean section; fetal death; neonatal outcomes in COVID 19; preterm birth; stillbirth; vertical transmission novel coronavirus
PMID:32311350DOI:10.1016/j.ajog.2020.04.013