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Am J Emerg Med . Frontal QRS/T angle can predict mortality in COVID-19 patients

tetano

Editor, Senior Moderator
Am J Emerg Med


. 2022 May 25;58:66-72.
doi: 10.1016/j.ajem.2022.05.034. Online ahead of print.
Frontal QRS/T angle can predict mortality in COVID-19 patients


Ramazan Gunduz[SUP] 1 [/SUP], Bekir Serhat Yildiz[SUP] 2 [/SUP], Su Ozgur[SUP] 3 [/SUP], Mehmet Burak Ozen[SUP] 4 [/SUP], Eren Ozan Bakir[SUP] 2 [/SUP], Ibrahim Halil Ozdemir[SUP] 4 [/SUP], Nurullah Cetin[SUP] 2 [/SUP], Songul Usalp[SUP] 5 [/SUP], Soner Duman[SUP] 3 [/SUP]



Affiliations

Abstract

Aims: The frontal QRS-T (fQRS) angle has been investigated in the general population, including healthy people and patients with heart failure. The fQRS angle can predict mortality due to myocarditis, ischaemic and non-ischaemic cardiomyopathies, idiopathic dilated cardiomyopathy, and chronic heart failure in the general population. Moreover, no studies to date have investigated fQRS angle in coronavirus disease 2019 (COVID-19) patients. Thus, the purpose of this retrospective multicentre study was to evaluate the fQRS angle of COVID-19 patients to predict in-hospital mortality and the need for mechanical ventilation.
Methods and results: An electrocardiogram was performed for 327 COVID-19 patients during admission, and the fQRS angle was calculated. Mechanical ventilation was needed in 119 patients; of them, 110 died in the hospital. The patients were divided into two groups according to an fQRs angle >90° versus an fQRS angle ≤90°. The percentages of mortality and the need for mechanical ventilation according to fQRS angle were 67.8% and 66.1%, respectively, in the fQRs >90° group and 26.1% and 29.9% in the fQRS ≤90°group. Heart rate, oxygen saturation, fQRS angle, estimated glomerular filtration rate, and C-reactive protein level were predictors of mortality on the multivariable analysis. The mortality risk increased 2.9-fold on the univariate analysis and 1.6-fold on the multivariate analysis for the fQRS >90° patient group versus the fQRS ≤90° group.
Conclusion: In conclusion, a wide fQRS angle >90° was a predictor of in-hospital mortality and associated with the need for mechanical ventilation among COVID-19 patients.

Keywords: COVID-19; Electrocardiogram; Frontal QRS angle; Mechanical ventilation; Mortality.
 
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