tetano
Editor, Senior Moderator
Am J Emerg Med
. 2021 Jan 4;S0735-6757(20)31169-4.
doi: 10.1016/j.ajem.2020.12.049. Online ahead of print.
COVID-19-associated pancytopenia and typhlitis
Furkan Ufuk[SUP] 1 [/SUP], Emre Bulgurcu[SUP] 2 [/SUP], Tugba Sari[SUP] 3 [/SUP]
Affiliations
Abstract
Neutropenic enterocolitis is also known as typhlitis, is characterized by severe inflammation in the bowel loops. It is often seen in immunosuppressed patients, and it has high morbidity and mortality. Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system and causes COVID-19 (Coronavirus Disease 2019), it may affect hematopoietic and gastrointestinal systems. Herein, we present a rare case of COVID-19-associated pancytopenia and typhlitis in a 60-year-old female who presented with abdominal pain. Contrast-enhanced abdominal computed tomography (CT) demonstrated the bowel wall thickening in the cecum and ascending colon compatible with enterocolitis. Moreover, the chest CT showed bilateral, peripheral, and multifocal ground-glass opacities, consistent with COVID-19 pneumonia. We also aimed to emphasize the laboratory, clinical, and CT findings of the patient.
Keywords: COVID-19; Computed tomography; Enterocolitis; Pancytopenia; Pneumonia.
. 2021 Jan 4;S0735-6757(20)31169-4.
doi: 10.1016/j.ajem.2020.12.049. Online ahead of print.
COVID-19-associated pancytopenia and typhlitis
Furkan Ufuk[SUP] 1 [/SUP], Emre Bulgurcu[SUP] 2 [/SUP], Tugba Sari[SUP] 3 [/SUP]
Affiliations
- PMID: 33446380
- DOI: 10.1016/j.ajem.2020.12.049
Abstract
Neutropenic enterocolitis is also known as typhlitis, is characterized by severe inflammation in the bowel loops. It is often seen in immunosuppressed patients, and it has high morbidity and mortality. Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system and causes COVID-19 (Coronavirus Disease 2019), it may affect hematopoietic and gastrointestinal systems. Herein, we present a rare case of COVID-19-associated pancytopenia and typhlitis in a 60-year-old female who presented with abdominal pain. Contrast-enhanced abdominal computed tomography (CT) demonstrated the bowel wall thickening in the cecum and ascending colon compatible with enterocolitis. Moreover, the chest CT showed bilateral, peripheral, and multifocal ground-glass opacities, consistent with COVID-19 pneumonia. We also aimed to emphasize the laboratory, clinical, and CT findings of the patient.
Keywords: COVID-19; Computed tomography; Enterocolitis; Pancytopenia; Pneumonia.