Advances in the structure and function of pandemic A/H1N1/2009 influenza virus HA protein

[tetano]

Bing Du Xue Bao. 2012 Jun;28(4):444-52.
[Advances in the structure and function of pandemic A/H1N1/2009 influenza virus HA protein].
[Article in Chinese]
Zhang WQ, Song SX, Wang TZ.
Source

Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Disease Control and Prevention, Shandong University Institute for Prevention Medicine, Jinan 250014, China. wenqiang782002@yahoo.com.cn
Abstract

Since March 2009, pandemic A/H1N1/2009 influenza virus has been spreading throughout many countries including China. The emerged virus caused great harm to human health and social economy. Hemagglutinin (HA) is the most important viral surface glycoprotein, mainly possessing three kinds of functions: (1) binding to host cell receptor, (2) triggering the fusion between viral envelop and target cell membrane, (3) stimulating the body to generate the neutralizing antibody. Advances in the structure, primary function, evolution and antigenicity of pandemic A/H1N1/2009 influenza virus HA protein are reviewed in this paper.

PMID:
22978172
[PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/22978172