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Acute necrotizing encephalopathy: a comparison between influenza and non-influenza cases

Emily

Emily

Editor, Senior Moderator
http://www.ncbi.nlm.nih.gov/pubmed/19457168
Microbiol Immunol. 2009 May;53(5):277-80. Epub 2009 Feb 9.
Acute necrotizing encephalopathy: a comparison between influenza and non-influenza cases.

Okumura A, Abe S, Kidokoro H, Mizuguchi M.

Department of Pediatrics, Juntendo University School of Medicine, Bunky-ku, Tokyo, Japan.
Abstract

The aim of this study was to clarify the difference between influenza and non-influenza cases in clinical symptoms, laboratory and neuroimaging findings, and outcome in children with ANE. We retrospectively studied 22 children with ANE. Eleven of them had virological proof of influenza infection and the other 11 were judged as non-influenza infection. There was no significant difference between influenza and non-influenza cases in sex, antipyretics use and neurological symptoms. Although laboratory data were not different between the two groups, brainstem lesions were relatively more frequent in influenza cases than in non-influenza cases. Outcome was not different between the two groups. The results of our study suggest that the pathogenesis of acute necrotizing encephalopathy will not be dependent on infectious agents.

PMID: 19457168 [PubMed - indexed for MEDLINE]
Click to expand...

There is a full text article here with more information. Pediatric ANE was recognized as a distinct disease in children in 1995 in Japan, about the same time as anti-NMDAR encephalitis.

http://jkms.org/search.php?where=aview&id=117745&code=0063JKMS&vmode=FULL
 
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