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Acceptance of vaccination during pregnancy: Experience with 2009 influenza A (H1N1) in the Netherlands

tetano

Editor, Senior Moderator
Vaccine

Available online 25 February 2012



Acceptance of vaccination during pregnancy: Experience with 2009 influenza A (H1N1) in the Netherlands

Alies van Liera, Corresponding author contact information, E-mail the corresponding author,
Anneke Steensa, E-mail the corresponding author,
Jos? A. Ferreirab, E-mail the corresponding author,
Nicoline A.T. van der Maasa, E-mail the corresponding author,
Hester E. de Melkera, E-mail the corresponding author

a Department of Epidemiology and Surveillance, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Postbox 1, 3720 BA Bilthoven, the Netherlands
b Expertise Centre for Methodology and Information Services, National Institute for Public Health and the Environment (RIVM), Postbox 1, 3720 BA Bilthoven, the Netherlands

Received 3 November 2011. Revised 9 February 2012. Accepted 13 February 2012. Available online 25 February 2012.

http://dx.doi.org/10.1016/j.vaccine.2012.02.030, How to Cite or Link Using DOI



In 2009, the Dutch government advised pregnant women to get vaccinated against influenza A (H1N1). A study was set up to gain insight into vaccination coverage and reasons why pregnant women seek vaccination or not.
Methods

We invited 14,529 pregnant women to complete an internet survey on vaccination during pregnancy in general and against 2009 influenza A (H1N1). Differences in background characteristics between unvaccinated and vaccinated women were investigated. Prediction analyses were carried out to determine which survey statement had the greatest impact on vaccination status or intention to get vaccinated during pregnancy.
Results

Of the 2993 included respondents, 63% reported to be vaccinated against 2009 influenza A (H1N1). Vaccination coverage was higher among older birth cohorts, women who had been pregnant before, women with underlying medical conditions, and women who reported no defined ?life philosophy?. Protection of the child (after birth), the government's advice and possible harmful effects of the vaccine for the unborn child had the greatest predictive value for vaccination status. With regards vaccination during future pregnancies, 39% had a positive intention to obtain vaccination and 45% were neutral. The government's advice was the strongest predictor for intention. Furthermore, women expressed concern over lack of sufficient knowledge about vaccine safety.
Conclusions

A considerable number of pregnant women in the Netherlands reported to be vaccinated against 2009 influenza A (H1N1). The challenge for the government in the future will be to provide pregnant women and health care professionals with sufficient and clear information about disease severity and the benefits and safety of vaccination.
Highlights

► We conducted an internet survey among pregnant women on vaccination during pregnancy. ► 63% reported to have received at least one vaccination against 2009 influenza A (H1N1). ► Protection of the child was the strongest predictor of this vaccination status. ► 39% reported a positive intention regarding vaccination during pregnancy in general. ► Following the advice of the government was the strongest predictor of this intention.


http://www.sciencedirect.com/science/article/pii/S0264410X12002137
 
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