AlaskaDenise
In Memoriam
I believe this is the location of their village - Kafr Hanut. There is another Hanut further east in another governate, but this appears to fill the bill...
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DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
- Thread starter AlaskaDenise
- Start date
AlaskaDenise
In Memoriam
Re: Egyptian govt reports 2 human bird flu cases
Re: Egyptian govt reports 2 human bird flu cases
What is standing between the current cases and a more easily transmitted virus?
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Re: Egyptian govt reports 2 human bird flu cases
What is standing between the current cases and a more easily transmitted virus?
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Re: Egyptian govt reports 2 human bird flu cases
Re: Egyptian govt reports 2 human bird flu cases
The earlier case was the first example of M230I in the Qinghai strain. It makes the H5N1 receptor binding domain look more like a human receptor binding domain. US NAMRU released the earlier sequence within a couple of days of confirmation. The sequence was public before the patient died. It will be interesting to see if the current cluster also has M230I. There are other changes circulating in the Qinghai strains in the Middle East, including S227N in Egypt. These acquisitions can recombine, and they have already been shown to synergize.
Re: Egyptian govt reports 2 human bird flu cases
AlaskaDenise said:
The earlier case was the first example of M230I in the Qinghai strain. It makes the H5N1 receptor binding domain look more like a human receptor binding domain. US NAMRU released the earlier sequence within a couple of days of confirmation. The sequence was public before the patient died. It will be interesting to see if the current cluster also has M230I. There are other changes circulating in the Qinghai strains in the Middle East, including S227N in Egypt. These acquisitions can recombine, and they have already been shown to synergize.
AlaskaDenise
In Memoriam
Re: Egyptian govt reports 2 human bird flu cases
Re: Egyptian govt reports 2 human bird flu cases
So this will be a "wait & see" how well the key (QSGRI) fits the lock?
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Re: Egyptian govt reports 2 human bird flu cases
So this will be a "wait & see" how well the key (QSGRI) fits the lock?
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
This is too much like Dogubayazit....both timing and new genetic changes.
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This is too much like Dogubayazit....both timing and new genetic changes.
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
The latest report from Reuters - see headlines thread - reports the cases were from a village near Zifta.
Zifta is about 6 miles south of Kafr Hanut.
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The latest report from Reuters - see headlines thread - reports the cases were from a village near Zifta.
Zifta is about 6 miles south of Kafr Hanut.
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Last edited:
AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
This will certainly bear watching.
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This will certainly bear watching.
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
If the 30F became ill on December 17th, then were the siblings infected via ducks or the 30 year old?
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If the 30F became ill on December 17th, then were the siblings infected via ducks or the 30 year old?
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
Theresa - your find about the NAMRU being next door to the hospital is great. Not only does the NAMRU do great work, but now they'll have the best possible circumstances for testing (perhaps even deposited from the air on their own property).
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Theresa - your find about the NAMRU being next door to the hospital is great. Not only does the NAMRU do great work, but now they'll have the best possible circumstances for testing (perhaps even deposited from the air on their own property).
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
In the case of the 15F reported today, it's interesting that they claim the tamilfu didn't help. Was it administered to late, or is the latest strain resistant?
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In the case of the 15F reported today, it's interesting that they claim the tamilfu didn't help. Was it administered to late, or is the latest strain resistant?
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
From Dutchy's article in the news thread....
What is the compensation program within Egypt?
The problem with compensation for each bird is that it may not compensate for the future food from their lost eggs.
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From Dutchy's article in the news thread....
What is the compensation program within Egypt?
The problem with compensation for each bird is that it may not compensate for the future food from their lost eggs.
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AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
While we're all anxiously awaiting news from the NAMRU in Cairo, here's a little history on the facility....
The U.S. Naval Medical Research Unit No.3 (NAMRU-3) conducts research and surveillance to support military personnel deployed to Africa, the Middle East, and Southwest Asia. The mission also includes the evaluation of vaccines, therapeutic agents, diagnostic assays, and vector control measures.
NAMRU-3 is adjacent to the Abbassia Fever Hospital, the oldest and largest fever hospital in the Middle East. NAMRU-3 has modem research laboratories, a medical research library, and is the only laboratory in Africa with an animal facility credited by the American Association for Accreditation of Laboratory Animal Care. It is the largest DoD overseas laboratory, with BSL-3 bio-containment space and field and hospital study sites located throughout Egypt. A malaria field site is located in the upper east region of northern Ghana.
NAMRU-3 works closely with the Egyptian Ministry of Health and Population, the U.S. National Institutes of Health, the World Health Organization, the U.S Agency for International Development and the U.S. Centers for Disease Control and Prevention. NAMRU-3 is a WHO Collaborating Center for HIV and Emerging Infectious Diseases.
NAMRU-3 established a presence in Egypt in 1942when the U.S. Typhus Commission placed a research laboratory staffed by American scientists and technicians in Cairo. The laboratory played a major role in averting a serious typhus outbreak during and following World War II. After the war, the Navy was invited by the Egyptian Government to continue collaborative studies of endemic tropical and subtropical diseases.
In response, NAMRU-3 was formally established in 1946.
http://www.nmrc.navy.mil/namru_3.htm
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While we're all anxiously awaiting news from the NAMRU in Cairo, here's a little history on the facility....
The U.S. Naval Medical Research Unit No.3 (NAMRU-3) conducts research and surveillance to support military personnel deployed to Africa, the Middle East, and Southwest Asia. The mission also includes the evaluation of vaccines, therapeutic agents, diagnostic assays, and vector control measures.
NAMRU-3 is adjacent to the Abbassia Fever Hospital, the oldest and largest fever hospital in the Middle East. NAMRU-3 has modem research laboratories, a medical research library, and is the only laboratory in Africa with an animal facility credited by the American Association for Accreditation of Laboratory Animal Care. It is the largest DoD overseas laboratory, with BSL-3 bio-containment space and field and hospital study sites located throughout Egypt. A malaria field site is located in the upper east region of northern Ghana.
NAMRU-3 works closely with the Egyptian Ministry of Health and Population, the U.S. National Institutes of Health, the World Health Organization, the U.S Agency for International Development and the U.S. Centers for Disease Control and Prevention. NAMRU-3 is a WHO Collaborating Center for HIV and Emerging Infectious Diseases.
NAMRU-3 established a presence in Egypt in 1942when the U.S. Typhus Commission placed a research laboratory staffed by American scientists and technicians in Cairo. The laboratory played a major role in averting a serious typhus outbreak during and following World War II. After the war, the Navy was invited by the Egyptian Government to continue collaborative studies of endemic tropical and subtropical diseases.
In response, NAMRU-3 was formally established in 1946.
http://www.nmrc.navy.mil/namru_3.htm
.
AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
the lack of biosecurity for these boys speaks volumes....
Boys stand on top of a pile of slaughtered birds to be buried, after an outbreak of bird flu killed one woman and infected two others, in the Egyptian village of Hanout in the Nile Delta December 25, 2006. An Egyptian woman died of bird flu on Sunday, hours after tests confirmed she and two other members of her extended family had been suffering from the highly pathogenic virus, a World Health Organization official said.
http://www.alertnet.org/db/crisisprofiles/BIRDFLU.htm
the lack of biosecurity for these boys speaks volumes....
Boys stand on top of a pile of slaughtered birds to be buried, after an outbreak of bird flu killed one woman and infected two others, in the Egyptian village of Hanout in the Nile Delta December 25, 2006. An Egyptian woman died of bird flu on Sunday, hours after tests confirmed she and two other members of her extended family had been suffering from the highly pathogenic virus, a World Health Organization official said.
http://www.alertnet.org/db/crisisprofiles/BIRDFLU.htm
AlaskaDenise
In Memoriam
Re: DISCUSSION - Hanut, Gharbiyah, Egypt - 12/23+
I contacted the NAMRU-3 about their reporting of influenza test results and received the following reply:
Denise,
As the WHO Regional Influenza Reference Laboratory I send all my results
to the WHO Headquarters via WHO-Eastern Mediterranean Regional Office.
I also inform other "customers" based on who in fact is the submitting
body. We attempt to post sequence data on Genebank within a week of
specimen processing. This allows for international transparency in
terms of what is circulating.
I hope this helps enlighten you as to our reporting channels.
Regards,
(name deleted per FT privacy policy)
Program Head, Virology
NAMRU-3 Cairo, Egypt
.
I contacted the NAMRU-3 about their reporting of influenza test results and received the following reply:
Denise,
As the WHO Regional Influenza Reference Laboratory I send all my results
to the WHO Headquarters via WHO-Eastern Mediterranean Regional Office.
I also inform other "customers" based on who in fact is the submitting
body. We attempt to post sequence data on Genebank within a week of
specimen processing. This allows for international transparency in
terms of what is circulating.
I hope this helps enlighten you as to our reporting channels.
Regards,
(name deleted per FT privacy policy)
Program Head, Virology
NAMRU-3 Cairo, Egypt
.