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Declan Butler - Bird flu outbreaks in Indonesia going unstudied

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Mingus

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http://www.nature.com/news/2006/060724/full/060724-12.html

News
Published online: 28 July 2006; | doi:10.1038/news060724-12
Bird flu outbreaks in Indonesia going unstudied
"No sequence data" have been acquired from birds for nearly a year.

Declan Butler


060724-12.jpg

Viral samples from Indonesian birds have only started arriving at official labs this month.
? Getty
Nature has learned that very few ? if any ? avian flu samples from Indonesian birds have been sent to official labs for sequencing over the past year.

The data blackout comes just as surveys of the country are revealing a startling number of previously unrecognized avian outbreaks.

"We have had no sequence data from poultry viruses for Indonesia for almost a year, since last August," says Peter Roeder, a consultant for the UN Food and Agriculture Organization (FAO) in Indonesia. "It just happened; no one was sending any samples," he says.

Experts say that without thorough genetic sequencing of bird viruses from the area it is difficult to tell whether the virus is mutating, or how the human cases correspond to birds in the area. There have been some human viruses found in Java that so far have no obvious avian counterparts: perhaps simply because matching strains in birds have not been sequenced, or perhaps not.

Good news?

Only now has a batch of such samples finally arrived at the World Organization for Animal Health (OIE) reference library in Geelong, Australia. "Good news: more than 100 animal isolates ready to go," reads a report from an international expert consultation on combating H5N1 in Indonesia, held in Jakarta in late June. Some 91 of these samples have now arrived, says Roeder.

This activity may have been spurred by the limited human-to-human spread of H5N1 seen within a family in Kubu Sembelang in May this year. Scientists are keen to compare the human viruses with previous avian outbreaks in the area, but no such recent samples have been available.

Reporting of poultry results from Indonesia is "inadequate", with "specimens going into a 'black box'", read the Jakarta meeting documents, adding that "this lack of information on avian H5N1 viruses requires urgent attention."

"Over the next few months there will be quite intensive genetic analysis of the samples," says Roeder. "This is something we really have to get on top of."

Under surveillance

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It has been difficult to organize sampling in Indonesia, Roeder says, with a decentralized system of responsibility for collecting viral material in a country spread over some 6,000 inhabited islands, with many backyard farms.

But that seems to be improving. There is an Indonesian government strategic plan, being assisted by the FAO, to create a large, coordinated surveillance and control programme around the country. A pilot scheme involving 12 teams has been running in the area around Jakarta since January this year.

The results of that pilot have proven startling. The Jakarta teams alone have discovered an average of 24 previously unknown infected locations a week between January and May. "The community surveillance system is starting to work," says Roeder.

Visit our newsblog to read and post comments about this story.
 
Re: Declan Butler - Bird flu outbreaks in Indonesia going unstudied

And from Declan butler's Blog


International community driving blindfolded in Indonesia flu battle
0 comments Published July 28th, 2006 in avian influenza, Neglected diseases.

Almost no avian flu poultry isolates have gone from Indonesia to the joint FAO/OIE network of national and international reference laboratories since summer 2005, I reveal in a short article tonight.

Some excerpts from the article:

??We have had no sequence data from poultry viruses for Indonesia for almost a year, since last August,? says Peter Roeder, a consultant for the UN Food and Agriculture Organization (FAO) in Indonesia. ?It just happened; no one was sending any samples,? he says.?

?Only now has a batch of such samples finally arrived at the World Organization for Animal Health (OIE) reference library in Geelong, Australia. ?Good news: more than 100 animal isolates ready to go,? reads a report from an international expert consultation on combating H5N1 in Indonesia, held in Jakarta in late June. Some 91 of these samples have now arrived, says Roeder.?

?Reporting of poultry results from Indonesia is ?inadequate?, with ?specimens going into a ?black box??, read the Jakarta meeting documents, adding that ?this lack of information on avian H5N1 viruses requires urgent attention.?"

The article also reveals how a pilot surveillance scheme involving 12 teams around Jakarta has picked up some 24 previously undetected infected villages a week since the start of the year. The scheme, which is now being rolled out across the archipelago risks quickly changing current maps of official outbreaks in the country:

?The community surveillance system is starting to work,? says Roeder, ?and bear in mind that here we were looking only at one small part of Java, there is a lot more H5N1 out there than is reflected in the official disease reporting system.?
 
INDONESIA - Bird flu outbreaks in Indonesia going unstudied [D. Butler]

INDONESIA - Bird flu outbreaks in Indonesia going unstudied [D. Butler]

Mingus -- you beat me by a couple of minutes! :p All I have to say about this report is: WTF?!?!?!

My favorite bits...


Nature has learned that very few — if any — avian flu samples from Indonesian birds have been sent to official labs for sequencing over the past year.

The data blackout comes just as surveys of the country are revealing a startling number of previously unrecognized avian outbreaks.

"We have had no sequence data from poultry viruses for Indonesia for almost a year, since last August," says Peter Roeder, a consultant for the UN Food and Agriculture Organization (FAO) in Indonesia. "It just happened; no one was sending any samples," he says.


Experts say that without thorough genetic sequencing of bird viruses from the area it is difficult to tell whether the virus is mutating, or how the human cases correspond to birds in the area. There have been some human viruses found in Java that so far have no obvious avian counterparts: perhaps simply because matching strains in birds have not been sequenced, or perhaps not.
Reporting of poultry results from Indonesia is "inadequate", with "specimens going into a 'black box'", read the Jakarta meeting documents, adding that "this lack of information on avian H5N1 viruses requires urgent attention."
The results of that pilot have proven startling. The Jakarta teams alone have discovered an average of 24 previously unknown infected locations a week between January and May [!!!]. "The community surveillance system is starting to work," says Roeder.
 
Re: Declan Butler - Bird flu outbreaks in Indonesia going unstudied

The article at Post #2 says:

"24 previously undetected infected villages a week."

For me that is a bit different than "24 previously undetected locations. (Post #1).
 
Re: Declan Butler - Bird flu outbreaks in Indonesia going unstudied

The results of that pilot have proven startling. The Jakarta teams alone have discovered an average of 24 previously unknown infected locations a week between January and May
Doing the math -- 22 weeks times the average 24 infected locations = 528 infected locations around Jakarta between January and May
 
Re: Declan Butler - Bird flu outbreaks in Indonesia going unstudied

i used 17 weeks as a comp since it doesn't specify, came up with 456. at what percentage of infected to tested? there must be some mistake in those numbers. thats appalling.
 
Re: Declan Butler - Bird flu outbreaks in Indonesia going unstudied

"pilot surveillance scheme" this phrase gives this article a negative, or nefarious slant.
 
Bird flu outbreaks in Indonesia going unstudied

Bird flu outbreaks in Indonesia going unstudied

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</TD></TR><TR xmlns=""><TD vAlign=top height=22>News

http://www.nature.com/news/2006/060724/full/060724-12.html
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</TD></TR><TR><TD>Published online: 28 July 2006; | doi:10.1038/news060724-12 Bird flu outbreaks in Indonesia going unstudied

"No sequence data" have been acquired from birds for nearly a year. Declan Butler
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</TD></TR><TR><TD class=ltpink>Viral samples from Indonesian birds have only started arriving at official labs this month.
? Getty</TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE>Nature has learned that very few ? if any ? avian flu samples from Indonesian birds have been sent to official labs for sequencing over the past year.

The data blackout comes just as surveys of the country are revealing a startling number of previously unrecognized avian outbreaks.

"We have had no sequence data from poultry viruses for Indonesia for almost a year, since last August," says Peter Roeder, a consultant for the UN Food and Agriculture Organization (FAO) in Indonesia. "It just happened; no one was sending any samples," he says.

Experts say that without thorough genetic sequencing of bird viruses from the area it is difficult to tell whether the virus is mutating, or how the human cases correspond to birds in the area. There have been some human viruses found in Java that so far have no obvious avian counterparts: perhaps simply because matching strains in birds have not been sequenced, or perhaps not.

Good news?

Only now has a batch of such samples finally arrived at the World Organization for Animal Health (OIE) reference library in Geelong, Australia. "Good news: more than 100 animal isolates ready to go," reads a report from an international expert consultation on combating H5N1 in Indonesia, held in Jakarta in late June. Some 91 of these samples have now arrived, says Roeder.

This activity may have been spurred by the limited human-to-human spread of H5N1 seen within a family in Kubu Sembelang in May this year. Scientists are keen to compare the human viruses with previous avian outbreaks in the area, but no such recent samples have been available.

Reporting of poultry results from Indonesia is "inadequate", with "specimens going into a 'black box'", read the Jakarta meeting documents, adding that "this lack of information on avian H5N1 viruses requires urgent attention."

"Over the next few months there will be quite intensive genetic analysis of the samples," says Roeder. "This is something we really have to get on top of."

Under surveillance

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</NOSCRIPT></TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE><!--end ad-->It has been difficult to organize sampling in Indonesia, Roeder says, with a decentralized system of responsibility for collecting viral material in a country spread over some 6,000 inhabited islands, with many backyard farms.

But that seems to be improving. There is an Indonesian government strategic plan, being assisted by the FAO, to create a large, coordinated surveillance and control programme around the country. A pilot scheme involving 12 teams has been running in the area around Jakarta since January this year.

The results of that pilot have proven startling. The Jakarta teams alone have discovered an average of 24 previously unknown infected locations a week between January and May. "The community surveillance system is starting to work," says Roeder.

Visit our newsblog to read and post comments about this story.

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