Paediatr Child Health. 2019 May;24(2):122-124. doi: 10.1093/pch/pxy085. Epub 2018 Jun 28.
Acute encephalopathy associated with influenza infection: Case report and review of the literature.
Albaker A1, Soder C2, Top KA3,4.
Author information
Abstract
Influenza has been associated with neurological complications. We describe the case of a toddler who presented with symptoms and signs of acute encephalopathy and hydrocephalus. Neuroimaging demonstrated cerebral edema and multifocal diffusion restriction in the thalamus and splenium of the corpus callosum. Influenza A was detected from the nasopharyngeal aspirate. The final diagnosis was acute influenza-associated encephalopathy. Despite treatment with a neuraminidase inhibitor and intravenous immune globulin, the toddler developed neurological sequelae. This case highlights a rare but severe complication of influenza in young children and the importance of influenza vaccination.
KEYWORDS:
Encephalitis; Encephalopathy; Influenza
PMID: 30996604 PMCID: PMC6462119 [Available on 2020-05-01] DOI: 10.1093/pch/pxy085
Acute encephalopathy associated with influenza infection: Case report and review of the literature.
Albaker A1, Soder C2, Top KA3,4.
Author information
Abstract
Influenza has been associated with neurological complications. We describe the case of a toddler who presented with symptoms and signs of acute encephalopathy and hydrocephalus. Neuroimaging demonstrated cerebral edema and multifocal diffusion restriction in the thalamus and splenium of the corpus callosum. Influenza A was detected from the nasopharyngeal aspirate. The final diagnosis was acute influenza-associated encephalopathy. Despite treatment with a neuraminidase inhibitor and intravenous immune globulin, the toddler developed neurological sequelae. This case highlights a rare but severe complication of influenza in young children and the importance of influenza vaccination.
KEYWORDS:
Encephalitis; Encephalopathy; Influenza
PMID: 30996604 PMCID: PMC6462119 [Available on 2020-05-01] DOI: 10.1093/pch/pxy085