Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,575 Posts: 2,831

Last Post: Influenza Other Respir Viruses . Neurologic Complications of Influenza and Potential Protective Vaccine Effects

2,575

2,831

Influenza Other Respir Viruses . Neurologic Complications of Influenza and Potential Protective Vaccine Effects

by tetano

March 8, 2025, 05:34 AM

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Immune response (26/60)	Host binding ability (223/276)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (136/140)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 72 Posts: 170

Last Post: Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

170

Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

by tetano

May 29, 2024, 03:56 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 257 Posts: 271

Last Post: ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

257

271

ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

by tetano

March 16, 2025, 01:22 AM

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Gut Microbes . Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection by tetano Started by tetano, March 9, 2024, 03:39 AM	0 responses 43 views 0 likes	Last Post by tetano March 9, 2024, 03:39 AM
J Virol . The H9N2 avian influenza virus increases APEC adhesion to oviduct epithelia by viral NS1 protein-mediated activation of the TGF-β pathway by tetano Started by tetano, March 2, 2024, 02:16 AM	0 responses 41 views 0 likes	Last Post by tetano March 2, 2024, 02:16 AM
iScience . Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates by tetano Started by tetano, February 28, 2024, 05:08 AM	0 responses 36 views 0 likes	Last Post by tetano February 28, 2024, 05:08 AM
Brief Bioinform . PREDAC-CNN: predicting antigenic clusters of seasonal influenza A viruses with convolutional neural network by tetano Started by tetano, February 14, 2024, 04:25 AM	0 responses 32 views 0 likes	Last Post by tetano February 14, 2024, 04:25 AM
Nat Commun . The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome by tetano Started by tetano, February 7, 2024, 03:45 AM	0 responses 31 views 0 likes	Last Post by tetano February 7, 2024, 03:45 AM
Microbiol Spectr . Swine influenza A virus isolates containing the pandemic H1N1 origin matrix gene elicit greater disease in the murine model by tetano Started by tetano, February 3, 2024, 04:07 AM	0 responses 50 views 0 likes	Last Post by tetano February 3, 2024, 04:07 AM
Virology . A neonatal piglet model reveals interactions between nasal microbiota and influenza A virus pathogenesis by tetano Started by tetano, February 3, 2024, 04:03 AM	0 responses 30 views 0 likes	Last Post by tetano February 3, 2024, 04:03 AM
Cell Host Microbe . Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection by tetano Started by tetano, February 2, 2024, 03:29 AM	0 responses 32 views 0 likes	Last Post by tetano February 2, 2024, 03:29 AM
PLoS One . A polarized cell system amenable to subcellular resolution imaging of influenza virus infection by tetano Started by tetano, January 27, 2024, 03:09 AM	0 responses 37 views 0 likes	Last Post by tetano January 27, 2024, 03:09 AM
iScience . Influenza A virus selectively elevates prostaglandin E2 formation in pro-resolving macrophages by tetano Started by tetano, January 24, 2024, 03:19 AM	0 responses 44 views 0 likes	Last Post by tetano January 24, 2024, 03:19 AM

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