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Curr Microbiol . Interaction Between SARS-CoV-2 and Pathogenic Bacteria

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  • Curr Microbiol . Interaction Between SARS-CoV-2 and Pathogenic Bacteria

    Curr Microbiol


    . 2023 May 24;80(7):223.
    doi: 10.1007/s00284-023-03315-y. Interaction Between SARS-CoV-2 and Pathogenic Bacteria

    Parvindokht Fazel # 1 2 , Hamid Sedighian # 3 , Elham Behzadi 4 , Reza Kachuei 5 , Abbas Ali Imani Fooladi 6



    AffiliationsAbstract

    The novel human coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which results in the coronavirus disease 2019 (COVID-19), has caused a serious threat to global public health. Therefore, many studies are performed on the causes and prevalence of this disease and the possible co-occurrence of the infection with other viral and bacterial pathogens is investigated. Respiratory infections predispose patients to co-infections and these lead to increased disease severity and mortality. Numerous types of antibiotics have been employed for the prevention and treatment of bacterial co-infection and secondary bacterial infections in patients with a SARS-CoV-2 infection. Although antibiotics do not directly affect SARS-CoV-2, viral respiratory infections often result in bacterial pneumonia. It is possible that some patients die from bacterial co-infection rather than virus itself. Therefore, bacterial co-infection and secondary bacterial infection are considered critical risk factors for the severity and mortality rates of COVID-19. In this review, we will summarize the bacterial co-infection and secondary bacterial infection in some featured respiratory viral infections, especially COVID-19.


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