Vaccines (Basel) . Prospects and Challenges in the Development of Universal Influenza Vaccines

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Vaccines (Basel)


. 2020 Jul 6;8(3):E361.
doi: 10.3390/vaccines8030361.
Prospects and Challenges in the Development of Universal Influenza Vaccines


Anders Madsen ¹ , Rebecca Jane Cox ^{1 2}



Affiliations

• PMID: 32640619
• DOI: 10.3390/vaccines8030361

Free article

Abstract

Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can target a broader range of influenza viruses. The development and licensure of a universal influenza vaccine could provide a game changing option for the control of influenza by protecting against all influenza A and B viruses. Here we review important findings and considerations regarding the development of universal influenza vaccines and what we can learn from this moving forward with a SARS-CoV-2 vaccine design.

Keywords: influenza; next-generation vaccine; vaccine.