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Influenza Other Respir Viruses. 2018 Jun 14. doi: 10.1111/irv.12585. [Epub ahead of print]
Influenza illness averted by influenza vaccination among school year children in Beijing, 2013-2016.
Zhang Y1,2,3, Cao Z4, Costantino V3, Muscatello DJ3, Chughtai AA3, Yang P1,2, Wang Q1,2, MacIntyre CR3,5.
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Abstract
BACKGROUND:
The benefit of school-based influenza vaccination policy has not been fully addressed in Beijing.
OBJECTIVES:
To evaluate the benefit of school-based influenza vaccination policy launched in Beijing.
METHODS:
Using existing surveillance and immunization data, we developed a dynamic transmission model to assess the impact of influenza vaccination in school-going children. The outcome was defined as the averted number of medically attended influenza illnesses and the prevented disease fraction to all children aged 5-14 years for the 2013/14, 2014/15, and 2015/16 seasons.
RESULTS:
We estimated that during the three consecutive influenza seasons, the averted number of medically attended influenza illnesses among children aged 5-14 years was around 104,000 (95% CI: 101,000-106,000), 23,000 (95% CI: 22,000-23,000), and 21,000 (95% CI: 21,000-22,000), respectively. Corresponding prevented fractions to all children aged 5-14 years were 76.3%, 38.5%, and 43.9%.
CONCLUSIONS:
In Beijing, school-based vaccinations reduced a substantial number of medically attended influenza illnesses despite seasonal variation in the prevented fraction. This is strong supportive evidence for the continuation of school-based vaccination programs to reduce the influenza burden in this age group. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Influenza; Models; Students; Vaccination
PMID: 29905021 DOI: 10.1111/irv.12585
Free full text
Influenza illness averted by influenza vaccination among school year children in Beijing, 2013-2016.
Zhang Y1,2,3, Cao Z4, Costantino V3, Muscatello DJ3, Chughtai AA3, Yang P1,2, Wang Q1,2, MacIntyre CR3,5.
Author information
Abstract
BACKGROUND:
The benefit of school-based influenza vaccination policy has not been fully addressed in Beijing.
OBJECTIVES:
To evaluate the benefit of school-based influenza vaccination policy launched in Beijing.
METHODS:
Using existing surveillance and immunization data, we developed a dynamic transmission model to assess the impact of influenza vaccination in school-going children. The outcome was defined as the averted number of medically attended influenza illnesses and the prevented disease fraction to all children aged 5-14 years for the 2013/14, 2014/15, and 2015/16 seasons.
RESULTS:
We estimated that during the three consecutive influenza seasons, the averted number of medically attended influenza illnesses among children aged 5-14 years was around 104,000 (95% CI: 101,000-106,000), 23,000 (95% CI: 22,000-23,000), and 21,000 (95% CI: 21,000-22,000), respectively. Corresponding prevented fractions to all children aged 5-14 years were 76.3%, 38.5%, and 43.9%.
CONCLUSIONS:
In Beijing, school-based vaccinations reduced a substantial number of medically attended influenza illnesses despite seasonal variation in the prevented fraction. This is strong supportive evidence for the continuation of school-based vaccination programs to reduce the influenza burden in this age group. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Influenza; Models; Students; Vaccination
PMID: 29905021 DOI: 10.1111/irv.12585
Free full text