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Nephron. 2017 Dec 12. doi: 10.1159/000485398. [Epub ahead of print]
Vaccination Practices in Pediatric Dialysis Patients Across Europe. A European Pediatric Dialysis Working Group and European Society for Pediatric Nephrology Dialysis Working Group Study.
Bakkaloğlu SA1, ?zdemir Atikel Y1, Paglialonga F2, Stefanidis CJ3, Askiti V3, Vidal E4, Ariceta G5, Melek E6, Verrina E7, Printza N8, Vondrak K9, Zurowska A10, Zagozdzon I10, Ekim M11, ?zmert EN12, Dufek S13, Jankauskiene A14, Schmitt CP15, L?vai E15, Vande Walle J16, Canpolat N17, Holtta T18, Fischbach M19, Klaus G20, Aufricht C21, Shroff R13, Edefonti A2.
Author information
Abstract
BACKGROUND:
Data on the immunization practices in pediatric chronic kidney disease (CKD) patients are scarce. The purpose of this study was to evaluate current vaccination practices for children on dialysis across European pediatric nephrology centers.
METHODS:
A total of 18 tertiary pediatric nephrology centers from 12 European countries were included in the study. The data on universal national immunization programs and immunization practices for children with chronic disease or risk were recorded from European Center for Disease Prevention and Control and the World Health Organization. The immunization practices and center protocols for monitoring antibody titers after vaccination in dialysis patients were obtained through a questionnaire.
RESULTS:
All centers included in the study recommended immunization against hepatitis B virus (HBV), diphtheria, tetanus, pertussis, Hemophilus influenzae type b (Hib), poliomyelitis, measles, mumps, rubella (MMR), and streptococcus pneumonia in dialysis patients. In 16 centers, dialysis patients were vaccinated against influenza virus annually. HBV protective antibody titers were measured in 17 centers (during dialysis period in 14 centers, during pre-renal transplantation preparations in 14 centers or in both times in 11 centers). Hepatitis A virus (HAV) was reported to be followed in 13 centers, in 8 centers during dialysis period, and in 11 centers during pre-RTx preparations. MMR and varicella-zoster virus (VZV) protective antibody titers were measured during the dialysis period or before renal transplantation (RTx) in 12 and 15 centers, respectively, and in 6 centers both titers were checked both times.
CONCLUSION:
There are variations in vaccination practice across Europe. Children with CKD, those undergoing dialysis, and transplant candidates should receive age-appropriate vaccinations before RTx as well as before the transition to adult nephrology clinics and antibody levels should be monitored to evaluate the immunization status before and after RTx.
? 2017 S. Karger AG, Basel.
KEYWORDS:
Children; Dialysis; Immunization; Vaccination
PMID: 29232664 DOI: 10.1159/000485398
Vaccination Practices in Pediatric Dialysis Patients Across Europe. A European Pediatric Dialysis Working Group and European Society for Pediatric Nephrology Dialysis Working Group Study.
Bakkaloğlu SA1, ?zdemir Atikel Y1, Paglialonga F2, Stefanidis CJ3, Askiti V3, Vidal E4, Ariceta G5, Melek E6, Verrina E7, Printza N8, Vondrak K9, Zurowska A10, Zagozdzon I10, Ekim M11, ?zmert EN12, Dufek S13, Jankauskiene A14, Schmitt CP15, L?vai E15, Vande Walle J16, Canpolat N17, Holtta T18, Fischbach M19, Klaus G20, Aufricht C21, Shroff R13, Edefonti A2.
Author information
Abstract
BACKGROUND:
Data on the immunization practices in pediatric chronic kidney disease (CKD) patients are scarce. The purpose of this study was to evaluate current vaccination practices for children on dialysis across European pediatric nephrology centers.
METHODS:
A total of 18 tertiary pediatric nephrology centers from 12 European countries were included in the study. The data on universal national immunization programs and immunization practices for children with chronic disease or risk were recorded from European Center for Disease Prevention and Control and the World Health Organization. The immunization practices and center protocols for monitoring antibody titers after vaccination in dialysis patients were obtained through a questionnaire.
RESULTS:
All centers included in the study recommended immunization against hepatitis B virus (HBV), diphtheria, tetanus, pertussis, Hemophilus influenzae type b (Hib), poliomyelitis, measles, mumps, rubella (MMR), and streptococcus pneumonia in dialysis patients. In 16 centers, dialysis patients were vaccinated against influenza virus annually. HBV protective antibody titers were measured in 17 centers (during dialysis period in 14 centers, during pre-renal transplantation preparations in 14 centers or in both times in 11 centers). Hepatitis A virus (HAV) was reported to be followed in 13 centers, in 8 centers during dialysis period, and in 11 centers during pre-RTx preparations. MMR and varicella-zoster virus (VZV) protective antibody titers were measured during the dialysis period or before renal transplantation (RTx) in 12 and 15 centers, respectively, and in 6 centers both titers were checked both times.
CONCLUSION:
There are variations in vaccination practice across Europe. Children with CKD, those undergoing dialysis, and transplant candidates should receive age-appropriate vaccinations before RTx as well as before the transition to adult nephrology clinics and antibody levels should be monitored to evaluate the immunization status before and after RTx.
? 2017 S. Karger AG, Basel.
KEYWORDS:
Children; Dialysis; Immunization; Vaccination
PMID: 29232664 DOI: 10.1159/000485398