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Cell. 2016 Jul 28;166(3):532-533. doi: 10.1016/j.cell.2016.07.023.
Broadening Horizons: New Antibodies Against Influenza.
Jackson KJ1, Boyd SD2.
Author information
Abstract
Seasonal influenza vaccine formulation efforts struggle to keep up with viral antigenic variation. Two studies now report engineered or naturally occurring human antibodies targeting the influenza hemagglutinin (HA) stem, with exceptional neutralizing breadth (Joyce et al., 2016; Kallewaard et al., 2016). Antibodies with similar structural features are elicited in multiple subjects, suggesting that modified vaccine regimens could provide broad protection.
Copyright ? 2016 Elsevier Inc. All rights reserved.
PMID: 27471961 DOI: 10.1016/j.cell.2016.07.023
[PubMed - as supplied by publisher]
Broadening Horizons: New Antibodies Against Influenza.
Jackson KJ1, Boyd SD2.
Author information
Abstract
Seasonal influenza vaccine formulation efforts struggle to keep up with viral antigenic variation. Two studies now report engineered or naturally occurring human antibodies targeting the influenza hemagglutinin (HA) stem, with exceptional neutralizing breadth (Joyce et al., 2016; Kallewaard et al., 2016). Antibodies with similar structural features are elicited in multiple subjects, suggesting that modified vaccine regimens could provide broad protection.
Copyright ? 2016 Elsevier Inc. All rights reserved.
PMID: 27471961 DOI: 10.1016/j.cell.2016.07.023
[PubMed - as supplied by publisher]