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prepandemic vaccine strains

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  • prepandemic vaccine strains

    the current prepandemic vaccine recommendation of WHA involves
    the hemagglutinin of strains:

    Viet Nam/1194/2004
    Viet Nam/1203/2004
    Thailand/16/2004
    Indonesia/5/2005
    Indonesia/CDC357/2006
    Indonesia/CDC625/2006
    Turkey/15/2006
    Whooping swan/Mongolia/244/2005
    Bar headed Gs/Qinghai/1A/2005
    Dk/Hunan/15/2004
    Anhui/1/2005
    Guangxi/1/2005
    HK/213/2003
    HK/156/97(H5N1)


    however, the most central strains are:

    21 Ck/HK/61.9/02
    21 WildDk/Guangdong/314/04
    22 Ck/HKi/86.3/02
    22 Ck/Henan/210/04
    22 Ck/Henan/12/04
    23 Dk/Guangxi/50/01
    23 swan/Guangxi/307/04
    23 Ck/Hubei/489/04
    23 Ck/Henan/01/04
    23 Ck/Jilin/hh/02
    23 swine/Guangxi/wz/04

    while vaccine similar strains score:

    27 HK/213/03
    28 VNM/1203/04
    29 VNM/1194/04
    39 IDN/CDC357/06
    30 Bar-headed Gs/Qinghai/59/05
    31 Guangxi/1/05
    32 Anhui/1/05
    33 Ck/Dairi/BPPVI/05

    after removing similar sequences we have scores:

    21 001 WildDk/Guangdong/314/04
    25 011 Dk/Guangdong/40/00
    25 010 Ck/Jiangsu/cz1/02
    26 003 cat/THA/KU-02/04
    26 002 Dk/Hubei/wp/03

    28 009 HK/213/03
    34 068 HK/156/97
    35 034 Ck/Dairi/BPPVI/05
    35 014 Bar-headed Gs/Qinghai/59/05



    so, I wonder why they didn't consider to include
    the hemagglutitine of

    21 Ck/HK/61.9/02
    21 WildDk/Guangdong/314/04
    22 Ck/Henan/12/04

    in their recommendations or testings ?!
    I'm interested in expert panflu damage estimates
    my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT
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