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Vaccine: WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to Septe

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  • Vaccine: WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to Septe

    Vaccine

    Volume 30, Issue 45, 5 October 2012, Pages 6461?6471
    Cover image
    WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to September 2011

    Alexander I. KlimovCorresponding author contact information, E-mail the corresponding author,
    Rebecca Garten,
    Colin Russell,
    Ian G. Barr,
    Terry G. Besselaar,
    Rod Daniels,
    Othmar G. Engelhardt,
    Gary Grohmann,
    Shigeyuki Itamura,
    Anne Kelso,
    John McCauley,
    Takato Odagiri,
    Derek Smith,
    Masato Tashiro,
    Xiyan Xu,
    Richard Webby,
    Dayan Wang,
    Zhiping Ye,
    Shu Yuelong,
    Wenqing Zhang,
    Nancy Cox,
    Writing Committee of the World Health Organization Consultation on Southern Hemisphere Influenza Vaccine Composition for 20121

    http://dx.doi.org/10.1016/j.vaccine.2012.07.089, How to Cite or Link Using DOI

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    Abstract

    In February and September each year the World Health Organisation (WHO) recommends influenza viruses to be included in influenza vaccines for the forthcoming winters in the Northern and Southern Hemispheres respectively. These recommendations are based on data collected by National Influenza Centres (NIC) through the Global Influenza Surveillance and Response System (GISRS) and a more detailed analysis of representative and potential antigenically variant influenza viruses from the WHO Collaborating Centres for Influenza (WHO CCs) and Essential Regulatory Laboratories (ERLs). This article provides a detailed summary of the antigenic and genetic properties of viruses and additional background data used by WHO experts during development of the recommendations for the 2012 Southern Hemisphere influenza vaccine composition.
    Highlights

    ► We provide data used for selection of the 2012 southern hemisphere influenza vaccine. ► Influenza activity for the 2011 southern hemisphere season was low or moderate. ► Co-circulation of A(H1N1)pdm09, A(H3N2) and influenza B viruses continued. ► No change was recommended for the 2012 vaccine composition comparing with 2011.

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