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Source: http://www.sciencedaily.com/releases...0403193735.htm
Children: Better Protection from Influenza With Improved Vaccine
ScienceDaily (Apr. 3, 2012) ? An intranasal vaccine that includes four weakened strains of influenza could do a better job in protecting children from the flu than current vaccines, Saint Louis University research shows.
Before each influenza season, scientists predict which strains of flu will be circulating and make a trivalent vaccine that includes three strains of influenza -- two of influenza A and one of influenza B.
The ability to add another strain of influenza B without compromising the vaccine's ability to protect against the other three strains will allow scientists make a better vaccine, said Robert Belshe, M.D., professor of infectious diseases at Saint Louis University School of Medicine and the corresponding author of the research article.
"The bottom line is adding another strain to make a quadrivalent vaccine improves our ability to protect against flu and doesn't reduce the body's immune response to the other strains," said Belshe, who also directs Saint Louis University's Center for Vaccine Development.
"It should bring us better protection because there's less guess work than in the standard trivalent vaccine..."
...Journal Reference:
1. Stan L. Block, Judith Falloon, Jeffrey A. Hirschfield, Leonard R. Krilov, Filip Dubovsky, Tingting Yi, Robert B. Belshe. The Immunogenicity and Safety of a Quadrivalent Live Attenuated Influenza Vaccine in Children. The Pediatric Infectious Disease Journal, 2012; : 1 DOI: 10.1097/INF.0b013e31825687b0
Children: Better Protection from Influenza With Improved Vaccine
ScienceDaily (Apr. 3, 2012) ? An intranasal vaccine that includes four weakened strains of influenza could do a better job in protecting children from the flu than current vaccines, Saint Louis University research shows.
Before each influenza season, scientists predict which strains of flu will be circulating and make a trivalent vaccine that includes three strains of influenza -- two of influenza A and one of influenza B.
The ability to add another strain of influenza B without compromising the vaccine's ability to protect against the other three strains will allow scientists make a better vaccine, said Robert Belshe, M.D., professor of infectious diseases at Saint Louis University School of Medicine and the corresponding author of the research article.
"The bottom line is adding another strain to make a quadrivalent vaccine improves our ability to protect against flu and doesn't reduce the body's immune response to the other strains," said Belshe, who also directs Saint Louis University's Center for Vaccine Development.
"It should bring us better protection because there's less guess work than in the standard trivalent vaccine..."
...Journal Reference:
1. Stan L. Block, Judith Falloon, Jeffrey A. Hirschfield, Leonard R. Krilov, Filip Dubovsky, Tingting Yi, Robert B. Belshe. The Immunogenicity and Safety of a Quadrivalent Live Attenuated Influenza Vaccine in Children. The Pediatric Infectious Disease Journal, 2012; : 1 DOI: 10.1097/INF.0b013e31825687b0
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