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Am J Public Health. 2012 Apr;102(4):596-605. Epub 2012 Feb 16.
Benefits and effectiveness of administering pneumococcal polysaccharide vaccine with seasonal influenza vaccine: an approach for policymakers.
Gilchrist SA, Nanni A, Levine O.
Source
Shawn A. N. Gilchrist is with S. Gilchrist Consulting Services, Brampton, Ontario, Canada. Angeline Nanni is with ALN Consulting, Ellicott City, MD. Orin Levine is with International Vaccine Access Center, and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Abstract
For the influenza pandemic of 2009-2010, countries responded to the direct threat of influenza but may have missed opportunities and strategies to limit secondary pneumococcal infections. Delivering both vaccines together can potentially increase pneumococcal polysaccharide vaccine (PPV23) immunization rates and prevent additional hospitalizations and mortality in the elderly and other high-risk groups. We used PubMed to review the literature on the concomitant use of PPV23 with seasonal influenza vaccines. Eight of 9 clinical studies found that a concomitant program conferred clinical benefits. The 2 studies that compared the cost-effectiveness of different strategies found concomitant immunization to be more cost-effective than either vaccine given alone. Policymakers should consider a stepwise strategy to reduce the burden of secondary pneumococcal infections during seasonal and pandemic influenza outbreaks.
PMID:
22397339
[PubMed - in process]
Benefits and effectiveness of administering pneumococcal polysaccharide vaccine with seasonal influenza vaccine: an approach for policymakers.
Gilchrist SA, Nanni A, Levine O.
Source
Shawn A. N. Gilchrist is with S. Gilchrist Consulting Services, Brampton, Ontario, Canada. Angeline Nanni is with ALN Consulting, Ellicott City, MD. Orin Levine is with International Vaccine Access Center, and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Abstract
For the influenza pandemic of 2009-2010, countries responded to the direct threat of influenza but may have missed opportunities and strategies to limit secondary pneumococcal infections. Delivering both vaccines together can potentially increase pneumococcal polysaccharide vaccine (PPV23) immunization rates and prevent additional hospitalizations and mortality in the elderly and other high-risk groups. We used PubMed to review the literature on the concomitant use of PPV23 with seasonal influenza vaccines. Eight of 9 clinical studies found that a concomitant program conferred clinical benefits. The 2 studies that compared the cost-effectiveness of different strategies found concomitant immunization to be more cost-effective than either vaccine given alone. Policymakers should consider a stepwise strategy to reduce the burden of secondary pneumococcal infections during seasonal and pandemic influenza outbreaks.
PMID:
22397339
[PubMed - in process]
