World J Radiol
. 2024 Sep 28;16(9):460-465.
doi: 10.4329/wjr.v16.i9.460. Behcet's disease-related panuveitis following COVID-19 vaccination: A case report
Rou-Ting Lin 1 2 , Pei-Kang Liu 3 4 , Chia-Wei Chang 2 , Kai-Chun Cheng 3 4 , Kuo-Jen Chen 5 , Yo-Chen Chang 3 4 6
Affiliations
Background: Behcet's disease (BD) is an inflammatory disorder known for various symptoms, including oral and genital ulcers and ocular inflammation. Panuveitis, a severe eye condition, is rare as the first sign of BD.
Case summary: We present an unusual case of a 30-year-old man who developed panuveitis after receiving the mRNA-based coronavirus disease 2019 (COVID-19) vaccine (Moderna). Laboratory tests ruled out infections, but he had a positive HLA-B51 result and a history of genital ulcer and oral ulcers, leading to a BD diagnosis. Treatment with corticosteroids improved his condition. Interestingly, he had another episode of panuveitis after the second mRNA vaccine dose, which also responded to corticosteroids.
Conclusion: This case highlights the rare onset of BD following mRNA COVID-19 vaccination, suggesting a potential link between these vaccines and BD's eye symptoms, emphasizing the importance of quick treatment in similar cases.
Keywords: Behcet’s disease; Case report; Ocular inflammation; Panuveitis; mRNA COVID-19 vaccine.
. 2024 Sep 28;16(9):460-465.
doi: 10.4329/wjr.v16.i9.460. Behcet's disease-related panuveitis following COVID-19 vaccination: A case report
Rou-Ting Lin 1 2 , Pei-Kang Liu 3 4 , Chia-Wei Chang 2 , Kai-Chun Cheng 3 4 , Kuo-Jen Chen 5 , Yo-Chen Chang 3 4 6
Affiliations
- PMID: 39355389
- PMCID: PMC11440273
- DOI: 10.4329/wjr.v16.i9.460
Background: Behcet's disease (BD) is an inflammatory disorder known for various symptoms, including oral and genital ulcers and ocular inflammation. Panuveitis, a severe eye condition, is rare as the first sign of BD.
Case summary: We present an unusual case of a 30-year-old man who developed panuveitis after receiving the mRNA-based coronavirus disease 2019 (COVID-19) vaccine (Moderna). Laboratory tests ruled out infections, but he had a positive HLA-B51 result and a history of genital ulcer and oral ulcers, leading to a BD diagnosis. Treatment with corticosteroids improved his condition. Interestingly, he had another episode of panuveitis after the second mRNA vaccine dose, which also responded to corticosteroids.
Conclusion: This case highlights the rare onset of BD following mRNA COVID-19 vaccination, suggesting a potential link between these vaccines and BD's eye symptoms, emphasizing the importance of quick treatment in similar cases.
Keywords: Behcet’s disease; Case report; Ocular inflammation; Panuveitis; mRNA COVID-19 vaccine.