Emerg Infect Dis
. 2021 Sep 24;27(12).
doi: 10.3201/eid2712.211772. Online ahead of print.
Limited Protection of Inactivated SARS-CoV-2 Vaccine against Wuhan Strain and Variants of Concern
Taweewun Hunsawong, Stefan Fernandez, Rome Buathong, Naretrit Khadthasrima, Kamonthip Rungrojchareonkit, Jindarat Lohachanakul, Rungarun Suthangkornkul, Kedsara Tayong, Angkana T Huang, Chonticha Klungthong, Piyawan Chinnawirotpisan, Yongyuth Poolpanichupatam, Anthony R Jones, Eric D Lombardini, Supaporn Wacharapluesadee, Opass Putcharoen
- PMID: 34559045
- DOI: 10.3201/eid2712.211772
Abstract
In vitro determination of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies induced in serum samples from recipients of the CoronaVac vaccine showed a short protection period against the original virus strain and limited protection against variants of concern. These data provide support for vaccine boosters, especially variants of concern circulate.
Keywords: COVID 19; SARS-CoV-2; Thailand; coronavirus disease; inactivated SARS-CoV-2 vaccine; neutralizing antibodies; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccination; viruses.