Clin Neurol Neurosurg . Acute disseminated encephalomyelitis after SARS-CoV-2 vaccination

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Clin Neurol Neurosurg


. 2021 Jul 21;208:106839.
doi: 10.1016/j.clineuro.2021.106839. Online ahead of print.
Acute disseminated encephalomyelitis after SARS-CoV-2 vaccination


Alberto Vogrig ¹ , Francesco Janes ² , Gian Luigi Gigli ³ , Francesco Curcio ⁴ , Ilaria Del Negro ⁵ , Serena D'Agostini ⁶ , Martina Fabris ⁴ , Mariarosaria Valente ³



Affiliations

• PMID: 34325334
• DOI: 10.1016/j.clineuro.2021.106839

Abstract

Several central and peripheral nervous system complications associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection have been recently described. An effective mass vaccination program is necessary to effectively reduce infection spread and, consequently, limit long-term sequelae, including those affecting the nervous system. Nevertheless, as more patients gain access to coronavirus disease 2019 (COVID-19) vaccines, it is important to report potential adverse events. Herein, we report a patient with previous history of post-infectious rhombencephalitis who developed an acute disseminated encephalomyelitis (ADEM) two weeks after being vaccinated for COVID-19.

Keywords: COVID-19; Encephalitis; Neurological adverse events; Neurological complications; Vaccine.