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Emerg Infect Dis
. 2021 Jun 8;27(8).
doi: 10.3201/eid2708.210887. Online ahead of print.
Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021
Pinkus Tober-Lau, Tatjana Schwarz, David Hillus, Jana Spieckermann, Elisa T Helbig, Lena J Lippert, Charlotte Thibeault, Willi Koch, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Stefanie Kasper, Friederike Münn, Frank Kunitz, Terry C Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Florian Kurth, Victor M Corman
- PMID: 34102098
- DOI: 10.3201/eid2708.210887
Abstract
One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.
Keywords: B cell; Berlin; COVID-19; Germany; SARS-CoV-2; T cell; antibody; coronavirus disease; immunity; mRNA; outbreak; phylogeny; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccine; viruses; zoonoses.