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BMC Pulm Med
. 2023 Nov 16;23(1):443.
doi: 10.1186/s12890-023-02743-7. Ventilator-associated pneumonia in Polish intensive care unit dedicated to COVID-19 patients
Marta Wałaszek 1 , Piotr Serwacki 2 , Zbigniew Cholewa 2 , Alicja Kosiarska 1 , Wioletta Świątek-Kwapniewska 2 , Małgorza Kołpa 1 , Elżbieta Rafa 3 , Róża Słowik 1 , Karolina Nowak 4 , Anna Różańska 5 , Jadwiga Wójkowska-Mach 4
Affiliations
Background: Healthcare-Associated Infections (HAI) are most frequently associated with patients in the Intensive Care Unit (ICU). Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), led to ICU hospitalization for some patients.
Methods: The study was conducted in 2020 and 2021 at a hospital in southern Poland. The Healthcare-Associated Infections Surveillance Network (HAI-Net) of the European Centre for Disease Prevention and Control (ECDC) was used for HAI diagnosis. The aim of this case-control study was to retrospectively assess the epidemiology of HAIs in ICU patients, distinguishing between COVID-19 and non-COVID-19 cases.
Results: The study included 416 ICU patients: 125 (30%) with COVID-19 and 291 (70%) without COVID-19, p < 0.05. The mortality rate was 80 (64%) for COVID-19 patients and 45 (16%) for non-COVID-19 patients, p < 0.001. Ventilator-Associated Pneumonia (VAP) occurred in 40 cases, with an incidence rate density of 6.3/1000 patient-days (pds): 14.1/1000 pds for COVID-19 patients vs. 3.6/1000 pds for non-COVID-19 patients. Odds Ratio (OR) was 2.297, p < 0.01. Acinetobacter baumannii was the most often isolated microorganism in VAP, with 25 cases (incidence rate 8.5%): 16 (18.2%) in COVID-19 patients vs. 9 (4.4%) in non-COVID-19 patients. OR was 4.814 (1.084-4.806), p < 0.001.
Conclusions: Patients treated in the ICU for COVID-19 faced twice the risk of VAP compared to non-COVID-19 patients. The predominant microorganism in VAP cases was Acinetobacter baumannii.
Keywords: COVID-19; Healthcare-associated pneumonia; Infection control; Mechanical ventilation.
. 2023 Nov 16;23(1):443.
doi: 10.1186/s12890-023-02743-7. Ventilator-associated pneumonia in Polish intensive care unit dedicated to COVID-19 patients
Marta Wałaszek 1 , Piotr Serwacki 2 , Zbigniew Cholewa 2 , Alicja Kosiarska 1 , Wioletta Świątek-Kwapniewska 2 , Małgorza Kołpa 1 , Elżbieta Rafa 3 , Róża Słowik 1 , Karolina Nowak 4 , Anna Różańska 5 , Jadwiga Wójkowska-Mach 4
Affiliations
- PMID: 37974141
- PMCID: PMC10652561
- DOI: 10.1186/s12890-023-02743-7
Background: Healthcare-Associated Infections (HAI) are most frequently associated with patients in the Intensive Care Unit (ICU). Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), led to ICU hospitalization for some patients.
Methods: The study was conducted in 2020 and 2021 at a hospital in southern Poland. The Healthcare-Associated Infections Surveillance Network (HAI-Net) of the European Centre for Disease Prevention and Control (ECDC) was used for HAI diagnosis. The aim of this case-control study was to retrospectively assess the epidemiology of HAIs in ICU patients, distinguishing between COVID-19 and non-COVID-19 cases.
Results: The study included 416 ICU patients: 125 (30%) with COVID-19 and 291 (70%) without COVID-19, p < 0.05. The mortality rate was 80 (64%) for COVID-19 patients and 45 (16%) for non-COVID-19 patients, p < 0.001. Ventilator-Associated Pneumonia (VAP) occurred in 40 cases, with an incidence rate density of 6.3/1000 patient-days (pds): 14.1/1000 pds for COVID-19 patients vs. 3.6/1000 pds for non-COVID-19 patients. Odds Ratio (OR) was 2.297, p < 0.01. Acinetobacter baumannii was the most often isolated microorganism in VAP, with 25 cases (incidence rate 8.5%): 16 (18.2%) in COVID-19 patients vs. 9 (4.4%) in non-COVID-19 patients. OR was 4.814 (1.084-4.806), p < 0.001.
Conclusions: Patients treated in the ICU for COVID-19 faced twice the risk of VAP compared to non-COVID-19 patients. The predominant microorganism in VAP cases was Acinetobacter baumannii.
Keywords: COVID-19; Healthcare-associated pneumonia; Infection control; Mechanical ventilation.