J Intensive Care Soc . Outcomes of critically ill COVID-19 patients managed in a high-volume severe respiratory failure and ECMO centre in the United Kingdom

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J Intensive Care Soc


. 2022 May;23(2):233-236.
doi: 10.1177/1751143720978850. Epub 2020 Dec 14.
Outcomes of critically ill COVID-19 patients managed in a high-volume severe respiratory failure and ECMO centre in the United Kingdom


Peter B Sherren ¹ , Luigi Camporota ¹ , Barnaby Sanderson ¹ , Andrew Jones ¹ , Manu Shankar-Hari ¹ , Chris Is Meadows ¹ , Nicholas Barrett ¹ , Marlies Ostermann ¹ , Nicholas Hart ¹



Affiliations

• PMID: 35615235
• PMCID: PMC9125444
• DOI: 10.1177/1751143720978850

Abstract

During the Coronavirus Disease 2019 (COVID-19) pandemic institutions have needed to develop pragmatic clinical pathways to balance the excess critical care demand and local resources. In this single-centre retrospective cohort study we describe the outcomes of COVID-19 patients admitted to Guy's and St. Thomas' NHS Foundation Trust (GSTT) critical care service. Patients were managed according to a local respiratory failure management pathway that was predicated on timely invasive ventilation when indicated and tailored ventilatory strategies according to pulmonary mechanics. Between 2 March and 25 May 2020 GSTT critical care service admitted 316 patients with confirmed COVID-19. Of the 201 patients admitted directly through the Emergency Department (ED) with a completed critical care outcome, 71.1% survived to critical care discharge. These favourable outcomes may serve to inform the wider debate on optimal organ support in COVID-19.

Keywords: ARDS; COVID-19; SARS-CoV-2; respiratory failure; ventilation.