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Heart Lung
. 2022 Jan 21;52:159-164.
doi: 10.1016/j.hrtlng.2022.01.012. Online ahead of print.
One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
Tufan Çınar 1 , Faysal Şaylık 2 , Tayyar Akbulut 2 , Suha Asal 3 , Murat Selçuk 3 , Vedat Çiçek 3 , Şahhan Kılıç 3 , Ahmet Lütfullah Orhan 3
Affiliations
- PMID: 35092905
- DOI: 10.1016/j.hrtlng.2022.01.012
Abstract
Background: There is a limited data about the one-year outcomes of patients diagnosed with acute coronary syndrome (ACS) and coronavirus disease 2019 (COVID-19).
Objectives: To assess one-year mortality of invasively managed patients with ACS and COVID-19 compared to ACS patients without COVID-19.
Methods: In our investigation, we defined the study time period as April 30 through September 1, 2020. The control groups consisted of ACS patients without COVID-19 at the same time period and ACS patients prior to the pandemic, within the same months as those of the study. COVID-19 infection was confirmed in all participants utilizing real-time polymerase chain reaction testing.
Results: This investigation examined 721 ACS participants in total. Among the participants, 119 patients were diagnosed with ACS and COVID-19, while 149 were diagnosed with ACS and without COVID-19. The other 453 ACS participants were diagnosed before the outbreak of the pandemic, within the same months as those of the study. One-year mortality rates were higher in the ACS participants with COVID-19 than in the ACS participants without COVID-19 and the pre-COVID-19 ACS participants (21.3% vs. 6.5% vs. 6.9%, respectively). An ACS along with COVID-19 was the only independent predictor of one-year mortality (HR=2.902, 95%CI=1.211-6.824, P = 0.018). According to the Kaplan-Meier survival curves, patients with ACS and COVID-19 had a lower chance of survival in the short-term and one-year periods.
Conclusion: This is believed to be the first study to report that ACS patients with COVID-19 had higher one-year risk of mortality compared to ACS patients without COVID-19.
Keywords: Acute coronary syndrome; COVID-19; One-year mortality.
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