Asia Pac J Clin Oncol
. 2021 Feb 19.
doi: 10.1111/ajco.13517. Online ahead of print.
Clinical features and prognosis of patients with COVID-19 after lung surgery: A retrospective clinical study
Jie Bai 1 , Hongling Chu 2 , Shaohua Ma 1 , Qinggang Ge 3
Affiliations
- PMID: 33609000
- DOI: 10.1111/ajco.13517
Abstract
Aim: To evaluate whether the history of lung surgery in patients was associated with poor prognosis of coronavirus disease 2019 (COVID-19).
Methods: Clinical data of patients with COVID-19 in a single-center were retrospectively analyzed. Patients with and without lung surgery were matched in 1:4 ratio to compare the differences in clinical characteristics, laboratory results, computed tomography findings, treatment regimens, and prognosis between them.
Results: Four patients had a history of lung surgery. The time from surgery to COVID-19 onset ranged from 3 to 10 days, with a median of 6.75 days. The mortality rate in the surgical group was higher than that in the nonsurgical group (25.0% vs. 6.3%).
Conclusion: Patients contracting COVID-19 after lung surgery presented a higher death rate; hence, it is necessary to omit lung surgery in patients with active COVID-19 infection.
Keywords: coronavirus disease 2019; immunosuppression; lung cancer; lung function; lung surgery.