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A A Pract . Nebulized Nitroglycerin for Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome: A Case Report

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  • A A Pract . Nebulized Nitroglycerin for Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome: A Case Report


    A A Pract


    . 2021 Feb 5;15(2):e01376.
    doi: 10.1213/XAA.0000000000001376.
    Nebulized Nitroglycerin for Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome: A Case Report


    Benjamin T Daxon 1 , Erin Lark 2 , Luke J Matzek 1 , Amanda R Fields 1 , Kyle J Haselton 1



    Affiliations

    Abstract

    We present a case where nitroglycerin tablets dissolved in saline and intravenous nitroglycerin solution were nebulized as surrogates for inhaled nitric oxide (iNO) after our iNO supply was depleted during the coronavirus disease 2019 (COVID-19) surge in New York. We gave this treatment to a COVID-19 patient with severe acute respiratory distress syndrome (ARDS) and hypercarbia. In response, the patient had immediate and clinically meaningful improvement in multiple organ systems despite no other interventions or ventilator changes.


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