Clin Transl Sci
. 2020 Sep 16.
doi: 10.1111/cts.12866. Online ahead of print.
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19)
Pablo Zubiaur 1 2 , Dora Koller 1 , Miriam Saiz-Rodr?guez 1 3 , Marcos Navares-G?mez 1 , Francisco Abad-Santos 1 2 4
Affiliations
- PMID: 32936528
- DOI: 10.1111/cts.12866
Abstract
In December 2019, the severe acute respiratory syndrome virus-2 pandemic began, causing the coronavirus disease 2019. A vast variety of drugs is being used off-label as potential therapies. Many of the repurposed drugs have clinical pharmacogenetic guidelines available with therapeutic recommendations when prescribed as indicated on the drug label. The aim of this review is to provide a comprehensive summary of pharmacogenetic biomarkers available for these drugs, which may help to prescribe them more safely.