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J Med Virol . A Retrospective Review of Memantine Use and COVID-19-associated Mortality From a National Database

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    J Med Virol . A Retrospective Review of Memantine Use and COVID-19-associated Mortality From a National Database


    J Med Virol


    . 2020 Jul 7.
    doi: 10.1002/jmv.26266. Online ahead of print.
    A Retrospective Review of Memantine Use and COVID-19-associated Mortality From a National Database


    Moon Ho Park 1 , Do Young Kwon 1



    Affiliations

    Abstract

    We read with interest the recent papers by Brenner and Cimolai regarding the therapeutic potential of memantine for coronavirus disease (COVID-19). In this retrospective, we investigated the relationship between treatment with memantine and COVID-19-associated mortality in 5,726 patients with COVID-19, of whom 140 had died. Our analysis revealed no association between memantine treatment and mortality in patients with COVID-19. However, we must explore all feasible options for preventing and treating COVID-19 due to the current lack of licensed vaccines or therapeutics for the disease. This article is protected by copyright. All rights reserved.

    Keywords: Antiviral agents < Disease control; Coronavirus < Virus classification; Drug specificity < Antiviral agents.

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