Einstein (Sao Paulo)


. 2020 Jun 3;18:eAE5793.
doi: 10.31744/einstein_journal/2020AE5793. eCollection 2020.
Intensive Support Recommendations for Critically-Ill Patients With Suspected or Confirmed COVID-19 Infection


[Article in English, Portuguese]

Thiago Domingos Corr?a 1 , Gustavo Faissol Janot de Matos 1 , Bruno de Arruda Bravim 1 , Ricardo Luiz Cordioli 1 , Alejandra Del Pilar Gallardo Garrido 1 , Murillo Santucci Cesar de Assuncao 1 , Carmen Silvia Valente Barbas 1 , Karina Tavares Timenetsky 1 , Roseny Dos Reis Rodrigues 1 , H?lio Penna Guimar?es 1 , Roberto Rabello Filho 1 , Frederico Polito Lomar 1 , Farah Christina de La Cruz Scarin 1 , Carla Luciana Batista 1 , Adriano Jos? Pereira 1 , Jo?o Carlos de Campos Guerra 1 , B?rbara Vieira Carneiro 1 , Ricardo Kenji Nawa 1 , Rodrigo Martins Brand?o 1 , Ant?nio Eduardo Pereira Pesaro 1 , Moacyr Silva J?nior 1 , Fabricio Rodrigues Torres de Carvalho 1 , Cilene Saghabi de Medeiros Silva 1 , Ana Claudia Ferraz de Almeida 1 , Marcelo Franken 1 , Marcele Liliane Pesavento 1 , Raquel Afonso Caserta Eid 1 , Leonardo Jos? Rolim Ferraz 1



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Abstract

In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, acute respiratory distress syndrome and acute renal failure and require intensive care. There is no randomized controlled clinical trial addressing potential therapies for patients with confirmed COVID-19 infection at the time of publishing these treatment recommendations. Therefore, these recommendations are based predominantly on the opinion of experts (level C of recommendation).