Eur J Case Rep Intern Med . Acalculous Acute Pancreatitis in a COVID-19 Patient

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Eur J Case Rep Intern Med


. 2020 May 13;7(6):001710.
doi: 10.12890/2020_001710. eCollection 2020.
Acalculous Acute Pancreatitis in a COVID-19 Patient


Pedro Antunes Meireles ^{1 2} , Filipe Bessa ¹ , Pedro Gaspar ^{1 3} , In?s Parreira ¹ , Virg?lio Dias Silva ^{1 4} , Catarina Mota ^{1 3} , Lourdes Alvoeiro ¹



Affiliations

• PMID: 32523925
• PMCID: PMC7279899
• DOI: 10.12890/2020_001710

Abstract

Coronavirus disease 2019 (COVID-19) is a multisystemic condition caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with manifestations ranging from mild upper respiratory symptoms to cytokine storm causing acute respiratory distress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARS-CoV-2 cell internalization. An increase in pancreatic enzymes has been increasingly recognized in patients with COVID-19, but little is known about the real prevalence of acute pancreatitis in this population. We report a case of acute acalculous pancreatitis in a COVID-19 patient.
Learning points: Acute pancreatitis may be a manifestation of SARS-CoV-2 infection.Future studies must address the real impact of pancreatic involvement in COVID-19 patients.

Keywords: SARS-CoV-2; acute pancreatitis; amylase; lipase.